Evidence map›Paper›PMID 35323335›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

Symptom Burden and Complexity in the Last 12 Months of Life among Cancer Patients Choosing Medical Assistance in Dying (MAID) in Alberta, Canada.

Linda Watson, Claire Link, Siwei Qi, Andrea DeIure, K Brooke Russell, Fiona Schulte, Caitlin Forbes, James Silvius, Brian Kelly, Barry D Bultz

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Linda WatsonCancer Care Alberta-Alberta Health Services, Calgary, AB T2S 3C3, Canada.ORCID 0000-0002-7802-0082
Claire LinkCancer Care Alberta-Alberta Health Services, Calgary, AB T2S 3C3, Canada.ORCID 0000-0001-6729-7898
Siwei QiCancer Care Alberta-Alberta Health Services, Calgary, AB T2S 3C3, Canada.
Andrea DeIureCancer Care Alberta-Alberta Health Services, Calgary, AB T2S 3C3, Canada.
K Brooke RussellDepartment of Psychology, University of Calgary, Calgary, AB T2N 1N4, Canada.ORCID 0000-0003-1190-7014
Fiona SchulteDepartment of Oncology, Division of Psychosocial Oncology, University of Calgary, Calgary, AB T2N 1N4, Canada.ORCID 0000-0002-3076-9676
Caitlin ForbesDepartment of Oncology, Division of Psychosocial Oncology, University of Calgary, Calgary, AB T2N 1N4, Canada.
James SilviusCumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada.ORCID 0000-0001-9648-801X
Brian KellyDepartment of Oncology, Division of Psychosocial Oncology, University of Calgary, Calgary, AB T2N 1N4, Canada.
Barry D BultzCancer Care Alberta-Alberta Health Services, Calgary, AB T2S 3C3, Canada.
Alberta Health Services · CAUniversity of Calgary · CA

Funding

Daniel Family Leadership Chair in Psychosocial Oncology N/A
6 · The paper itself

Abstract

backgroundIn 2019, cancer patients comprised over 65% of all individuals who requested and received Medical Assistance in Dying (MAID) in Canada. This descriptive study sought to understand the self-reported symptom burden and complexity of cancer patients in the 12 months prior to receiving MAID in Alberta.

methodsBetween July 2017 and January 2019, 337 cancer patients received MAID in Alberta. Patient characteristics were descriptively analyzed. As such, 193 patients (57.3%) completed at least one routine symptom-reporting questionnaire in their last year of life. Mixed effects models and generalized estimating equations were utilized to examine the trajectories of individual symptoms and overall symptom complexity within the cohort over this time.

resultsThe results revealed that all nine self-reported symptoms, and the overall symptom complexity of the cohort, increased as patients' MAID provision date approached, particularly in the last 3 months of life. While less than 20% of patients experienced high symptom complexity 12 months prior to MAID, this increased to 60% in the month of MAID provision.

conclusionsCancer patients in this cohort experienced increased symptom burden and complexity leading up to their death. These findings could serve as a flag to clinicians to closely monitor advanced cancer patients' symptoms, and provide appropriate support and interventions as needed.

Indexed as

NeoplasmsSuicide, AssistedAlbertaHumansMedical AssistanceSurveys and QuestionnairesMAIDMedical Aid in DyingMedical Assistance in Dyingmedically assisted deathPatient-Reported Outcomessymptom burdensymptom complexitysymptom management

Identifiers

PMID35323335
PMCPMC8947648
OpenAlexW4214949944

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.