Evidence map›Paper›PMID 35323198›Full record

ArticleInternational journal of neonatal screening2022

Delivering Positive Newborn Screening Results: Cost Analysis of Existing Practice versus Innovative, Co-Designed Strategies from the ReSPoND Study.

Francesco Fusco, Jane Chudleigh, Pru Holder, James R Bonham, Kevin W Southern, Alan Simpson, Louise Moody, Ellinor K Olander, Holly Chinnery, Stephen Morris

Abstract read
In one paragraph

Article in International journal of neonatal screening, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Francesco FuscoDepartment of Public Health and Primary Care, University of Cambridge, Cambridge CB2 0SR, UK.ORCID 0000-0001-5515-3977
Jane ChudleighCentre for Maternal and Child Health Research, City, University of London, London EC1V 0HB, UK.ORCID 0000-0002-7334-8708
Pru HolderCentre for Maternal and Child Health Research, City, University of London, London EC1V 0HB, UK.
James R BonhamPharmacy, Diagnostics and Genetics Sheffield Children's NHS Foundation Trust, Sheffield S10 2TH, UK.
Kevin W SouthernWomen's and Children's Health, University of Liverpool, Liverpool L69 3BX, UK.
Alan SimpsonFlorence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London SE1 8WA, UK.
Louise MoodyCentre for Arts, Memory and Communities, Coventry University, Coventry CV1 5FB, UK.ORCID 0000-0003-2326-4124
Ellinor K OlanderCentre for Maternal and Child Health Research, City, University of London, London EC1V 0HB, UK.
Holly ChinneryFaculty of Sports, Health and Applied Science, St Mary's University Twickenham, Twickenham TW1 4SX, UK.ORCID 0000-0002-3454-1505
Stephen MorrisDepartment of Public Health and Primary Care, University of Cambridge, Cambridge CB2 0SR, UK.

Funding

National Institute for Health Research 16/52/25
6 · The paper itself

Abstract

Although the communication pathways of Newborn Bloodspot Screening (NBS) are a delicate task, these pathways vary across different conditions and are often not evidence-based. The ReSPoND interventions were co-designed by healthcare professionals alongside parents who had received a positive NBS result for their child. To calculate the cost of these co-designed strategies and the existing communication pathways, we interviewed 71 members of the clinical and laboratory staff of the 13 English NBS laboratories in the English National Health Service. Therefore, a scenario analysis was used to compare the cost of the existing communication pathways to the co-designed strategies delivered by (i) home-visits and (ii) telecommunications. On average, the existing communication pathway cost £447.08 per infant (range: £237.12 to £628.51) or £234,872.75 (£3635.99 to £1,932,986.23) nationally. Implementing the new interventions relying on home-visits exclusively would cost on average £521.62 (£312.84 to £646.39) per infant and £297,816.03 (£4506.37 to £2,550,284.64) nationally, or £447.19 (£235.79 to £552.03) and £231,342.40 (£3923.7 to £1,922,192.22) if implemented via teleconsultations, respectively. The new strategies delivered are not likely to require additional resources compared with current practice. Further research is needed to investigate whether this investment represents good value for money for the NHS budget.

Indexed as

geneticshealth economicshealth services research

Identifiers

PMID35323198
PMCPMC8951105

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.