Evidence map›Paper›PMID 35323175›Full record

ArticleHematology reports2022

Joint Pain and Arthritis as First Clinical Manifestation of Systemic Amyloidosis and Multiple Myeloma: Case Report and Brief Literature Review.

Francesco Mazziotta, Gabriele Buda, Maria Livia Del Giudice, Enrico Orciuolo, Edoardo Benedetti, Matilde Masini, Vincenzo De Tata, Sara Galimberti, Mario Petrini

Open access · goldAbstract readCase Reports
In one paragraph

Article in Hematology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Francesco MazziottaHematology Division, Pisa University Hospital, 56126 Pisa, Italy.
Gabriele BudaHematology Division, Pisa University Hospital, 56126 Pisa, Italy.
Maria Livia Del GiudiceHematology Division, Pisa University Hospital, 56126 Pisa, Italy.ORCID 0000-0003-4291-8875
Enrico OrciuoloHematology Division, Pisa University Hospital, 56126 Pisa, Italy.
Edoardo BenedettiHematology Division, Pisa University Hospital, 56126 Pisa, Italy.ORCID 0000-0001-5295-2087
Matilde MasiniDepartment of Translational Research and New Technologies in Medicine and Surgery, Pisa University Hospital, 56126 Pisa, Italy.
Vincenzo De TataDepartment of Translational Research and New Technologies in Medicine and Surgery, Pisa University Hospital, 56126 Pisa, Italy.
Sara GalimbertiHematology Division, Pisa University Hospital, 56126 Pisa, Italy.
Mario PetriniHematology Division, Pisa University Hospital, 56126 Pisa, Italy.ORCID 0000-0002-1017-6961
University of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyloidosis is a rare disease that is often seen in conjunction with multiple myeloma (MM). Its damage varies depending on the anatomical site affected; however, it is believed that many cases of amyloidosis are misrecognized due to the fact that its signs and symptoms are nonspecific. Joint amyloidosis, in particular, may be confused with degenerative or autoimmune diseases. When it is associated with MM, it can significantly precede the diagnosis of the latter. We describe a case report of a woman of Nigerian heritage diagnosed with MM with widespread joint manifestations compatible with a diagnosis of amyloidosis, which had preceded the diagnosis of MM and benefited from MM treatment. Faced with the suspicion of amyloidosis, if confirmed, this can be used to anticipate the diagnosis of MM, and at a more advanced stage, it can benefit from the treatment of the MM.

Indexed as

immunoglobulin light-chain amyloidosisjoint diseasesmultiple myelomaplasma cell neoplasm

Identifiers

PMID35323175
PMCPMC8955677
OpenAlexW4214928714

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.