Evidence map›Paper›PMID 35323119›Full record

ArticleJournal of medical Internet research2022

Internet-Delivered Cognitive Behavioral Therapy for Generalized Anxiety Disorder in Nationwide Routine Care: Effectiveness Study.

Ville Ritola, Jari Olavi Lipsanen, Satu Pihlaja, Eero-Matti Gummerus, Jan-Henry Stenberg, Suoma Saarni, Grigori Joffe

Open access · goldAbstract read
In one paragraph

Article in Journal of medical Internet research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

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  17. Effectiveness of mobile-delivered, therapist-assisted cognitive behavioral therapy for insomnia in nationwide routine clinical care in Finland.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ville RitolaDepartment of Psychiatry, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID 0000-0001-9065-4347
Jari Olavi LipsanenDepartment of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.ORCID 0000-0003-0746-2745
Satu PihlajaDepartment of Psychiatry, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID 0000-0002-2402-6956
Eero-Matti GummerusDepartment of Psychiatry, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID 0000-0001-7485-4429
Jan-Henry StenbergDepartment of Psychiatry, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID 0000-0003-1327-7757
Suoma SaarniDepartment of Psychiatry, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID 0000-0003-3555-9958
Grigori JoffeDepartment of Psychiatry, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID 0000-0002-0782-6812
University of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTherapist-supported, internet-delivered cognitive behavioral therapy (iCBT) is efficacious for generalized anxiety disorder (GAD), but few studies are yet to report its effectiveness in routine care.

objectiveIn this study, we aim to examine whether a new 12-session iCBT program for GAD is effective in nationwide routine care.

methodsWe administered a specialized, clinic-delivered, therapist-supported iCBT for GAD in 1099 physician-referred patients. The program was free of charge for patients, and the completion time was not predetermined. We measured symptoms with web-based questionnaires. The primary measure of anxiety was the GAD 7-item scale (GAD-7); secondary measures were, for pathological worry, the Penn State Worry Questionnaire and, for anxiety and impairment, the Overall Anxiety Severity and Impairment Scale.

resultsPatients completed a mean 7.8 (SD 4.2; 65.1%) of 12 sessions, and 44.1% (485/1099) of patients completed all sessions. The effect size in the whole sample for GAD-7 was large (Cohen d=0.97, 95% CI 0.88-1.06). For completers, effect sizes were very large (Cohen d=1.34, 95% CI 1.25-1.53 for GAD-7; Cohen d=1.14, 95% CI 1.00-1.27 for Penn State Worry Questionnaire; and Cohen d=1.23, 95% CI 1.09-1.37 for Overall Anxiety Severity and Impairment Scale). Noncompleters also benefited from the treatment. Greater symptomatic GAD-7-measured relief was associated with more completed sessions, older age, and being referred from private or occupational care. Of the 894 patients with a baseline GAD-7 score ≥10, approximately 421 (47.1%) achieved reliable recovery.

conclusionsThis nationwide, free-of-charge, therapist-supported HUS Helsinki University Hospital-iCBT for GAD was effective in routine care, but further research must establish effectiveness against other treatments and optimize the design of iCBT for GAD for different patient groups and individual patients.

Indexed as

Anxiety DisordersCognitive Behavioral TherapyAnxietyHumansInternetTreatment OutcomeCBTcognitive behavioral therapydigital healthgeneralized anxiety disorderiCBTinternetmental healthroutine careweb-based

Identifiers

PMID35323119
PMCPMC8990365
OpenAlexW4205339579

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.