ArticleJournal of applied physiology (Bethesda, Md. : 1985)2022
Using pulmonary gas exchange to estimate shunt and deadspace in lung disease: theoretical approach and practical basis.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 12 citations in OpenAlex.
- Shunt estimation in pneumonia of different aetiologies: a non-invasive physiological assessment.BMJ open respiratory research · 2026Article
- Alveolar deadspace and intrapulmonary shunt in healthy individuals and in individuals who have recovered from COVID-19 infection.Experimental physiology · 2026Article
- Trying to disentangle the causes of dyspnea and exercise limitation in a subject with GATA2 deficiency and normal spirometry: a case report.Frontiers in physiology · 2026Article
- Machine Learning Techniques for the Analysis of the Influence of Blood Gasometry Parameters on Acid-Base Homeostasis in Pediatric Patients.Diagnostics (Basel, Switzerland) · 2025Article
- Assessment of the Rapid Shallow Breathing Index, Integrative Weaning Index, and Dead Space to Tidal Volume Ratio by Respiratory Failure Type in Successfully Weaned Emergency Department Patients.Medicina (Kaunas, Lithuania) · 2025Article
- Advances in gas-exchange physiology and pathophysiology.ERS monograph · 2025Article
- Increased intrapulmonary shunt and alveolar dead space post-COVID-19.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Article
- A modal definition of ideal alveolar oxygen.Physiological reports · 2023Article
- Intrapulmonary shunt and alveolar dead space in a cohort of patients with acute COVID-19 pneumonitis and early recovery.The European respiratory journal · 2023Article
- Novel gas exchange analysis in COVID-19 lung disease.The European respiratory journal · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The common pulmonary consequence of SARS-CoV-2 infection is pneumonia, but vascular clot may also contribute to COVID pathogenesis. Imaging and hemodynamic approaches to identifying diffuse pulmonary vascular obstruction (PVO) in COVID (or acute lung injury generally) are problematic particularly when pneumonia is widespread throughout the lung and hemodynamic consequences are buffered by pulmonary vascular recruitment and distention. Although stimulated by COVID-19, we propose a generally applicable bedside gas exchange approach to identifying PVO occurring alone or in combination with pneumonia, addressing both its theoretical and practical aspects. It is based on knowing that poorly (or non) ventilated regions, as occur in pneumonia, affect O
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.