Evidence map›Paper›PMID 35322930›Full record

ArticleActa ophthalmologica2022

Ocular surface health of the Finnish elderly population.

Ulla Aapola, Janika Nättinen, Ilona Suurkuukka, Jaakko Tuomilehto, Sirkka Keinänen-Kiukaanniemi, Jouko Saramies, Hannu Uusitalo

Open access · hybridAbstract read
In one paragraph

Article in Acta ophthalmologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
  3. Impact of signs and symptoms of dry eye disease on health-related quality of life: a cross-sectional population study among older adults.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Ulla Aapola *SILK, Department of Ophthalmology, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Janika Nättinen *SILK, Department of Ophthalmology, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID https://orcid.org/0000-0002-7844-079X
Ilona SuurkuukkaSouth Karelia Social and Health Care District, South Karelia, Finland.
Jaakko TuomilehtoPublic Health Promotion Unit, Finnish Institute for Health and Welfare, Helsinki, Finland.
Sirkka Keinänen-KiukaanniemiCenter for Life Course Health Research, University of Oulu, Oulu, Finland.
Jouko SaramiesSouth Karelia Social and Health Care District, South Karelia, Finland.
Hannu UusitaloSILK, Department of Ophthalmology, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Tampere University of Applied Sciences · FIEtelä-Karjalan sosiaali ja terveyspiiri · FIKing Abdulaziz University · SAUniversity of Oulu · FI

Funding

Business FinlandCompetitive State Research Financing of the Expert Responsibility area of Helsinki University HospitalElsemay Björn FundGlaukooma Tukisäätiö LuxPirkanmaan Rahasto
6 · The paper itself

Abstract

purposeThe aim of this study was to describe the clinical ocular surface characteristics in a population-based sample of Finnish elderly people.

methodsThis cross-sectional study included 601 subjects (335 females, 266 males) born between the years 1933-1956 and living in Savitaipale, Finland. Ocular surface health was evaluated using a comprehensive set of diagnostic tests. Previous dry eye (DE) diagnosis and history of drug treatment of DE were also recorded. Differences between sexes were estimated with Wilcoxon rank sum test and Fisher's exact test.

resultsOverall, 10% and 33% of people displayed signs of DE and ocular surface disease (OSD), respectively, and 30% had been previously diagnosed with DE and 36% used some form of drugs for DE. Men displayed more severe signs of meibomian gland dysfunction, blepharitis and conjunctival redness (p < 0.001), while women had higher scores in corneal staining (p = 0.005) and OSD Index (p < 0.001).

conclusionSigns of OSD and DE are common among the Finnish elderly population. However, the diagnosis is affected by the diagnostic criteria used and significant differences exist between sexes. Although women were more frequently diagnosed with DE and OSD and experienced more ocular surface irritation, men had more often lid and meibomian gland-related issues. The current diagnostic criteria of DE pose a risk of misclassifying men, who commonly display less severe symptoms in comparison with women yet exhibit more severe clinical signs associated especially with the lid margin.

Indexed as

Dry Eye SyndromesAgedCross-Sectional StudiesFemaleFinlandHumansMaleMeibomian GlandsTearsdry eye diseaseepidemiologyocular surface diseaseprevalence

Identifiers

PMID35322930
PMCPMC9790390
OpenAlexW4221070686

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.