Evidence map›Paper›PMID 35322846›Full record

ReviewChemical communications (Cambridge, England)2022

Recent developments in DNA-based mechanical nanodevices.

Qian Tian, Puspam Keshri, Mingxu You

Abstract readReview
In one paragraph

Review in Chemical communications (Cambridge, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Electrochemical DNA-based sensors for measuring cell-generated forces.bioRxiv : the preprint server for biology · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Qian TianDepartment of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003, USA. mingxuyou@umass.edu.
Puspam KeshriDepartment of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003, USA. mingxuyou@umass.edu.
Mingxu YouDepartment of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003, USA. mingxuyou@umass.edu.ORCID http://orcid.org/0000-0002-5279-2340

Funding

Defining Mechanical Landscapes at Cell-Cell JunctionsR35GM133507 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Mingxu You · 2019 to 2026
$2.8M
NIGMS NIH HHS R35 GM133507
6 · The paper itself

Abstract

Cellular processes and functions can be regulated by mechanical forces. Nanodevices that can measure and manipulate these forces are critical tools in chemical and cellular biology. Synthetic DNA oligonucleotides have been used to develop a wide range of powerful nanodevices due to their programmable nature and precise and predictable self-assembly. In recent years, various types of DNA-based mechanical nanodevices have been engineered for studying molecular-level forces. With the help of these nanodevices, our understanding of cellular responses to physical forces has been significantly advanced. In this article, we have reviewed some recent developments in DNA-based mechanical sensors and regulators for application in the characterization of cellular biomechanics and the manipulation of cellular morphology, motion and other functions. The design principles discussed in this article can be further used to inspire other types of powerful DNA-based mechanical nanodevices.

Indexed as

DNAOligonucleotidesMechanical PhenomenaDNAOligonucleotides

Identifiers

PMID35322846
PMCPMC9007884

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.