ArticleScientific reports2022
Changes in adverse pregnancy outcomes in women with advanced maternal age (AMA) after the enactment of China's universal two-child policy.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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30 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Prevalence of placenta previa among deliveries: An update systematic review and meta-analysis after the introduction of the two-child policy in Mainland China.Journal of global health · 2024Pooled it
- Association between gestational weight gain and adverse pregnancy outcomes in advanced maternal age: a retrospective cohort study.BMC pregnancy and childbirth · 2026Article
- Analysis of adverse pregnancy outcomes among pregnant women in Hunan Province from 2015 to 2023: Incidence, temporal trends, and risk factors.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026Article
- Assessing the impact of China's universal two-child policy on infant health: evidence from a quasi-experimental study.European journal of public health · 2026Article
- Comparison status and factors of pregnancy stress among pregnant women with second child between advanced maternal age and reproductive age: a cross-sectional study.BMC pregnancy and childbirth · 2026Article
- Risk factors for preterm birth in advanced maternal age pregnancies: a retrospective study.BMC pregnancy and childbirth · 2026Review
- The China Birth Cohort-Environmental and Genetic Factors (CBC-EG) Study: Design, Aims, Protocol, Findings, and Prospects.Environment & health (Washington, D.C.) · 2026Review
- Trends in maternal mortality in China and Hainan Province: an analysis based on GBD 2023 and Hainan surveillance data.Frontiers in global women's health · 2026Article
- Network analysis of spousal support and fear of childbirth in pregnant women of advanced maternal age.Frontiers in psychiatry · 2026Article
- Temporal trend and influencing factors of high-risk pregnancy in China: a nationwide longitudinal analysis.Frontiers in public health · 2026Article
- Association between the serum uric acid-to-creatinine ratio index and the risk of preeclampsia in advanced maternal age pregnant women: a retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
- Factors associated with self-management behavior among pregnant women with diet-controlled gestational diabetes mellitus in China: A cross-sectional study.Belitung nursing journal · 2026Article
- The optimal childbearing age and birth spacing in china: a multicenter retrospective cohort study.BMC public health · 2025Article
- Association between parity and adverse maternal and neonatal outcomes: a population-based cross-sectional study.Frontiers in medicine · 2025Article
- Temporal trend and factors of C-section and its impact on subsequent pregnancy outcomes in Central China.Frontiers in medicine · 2025Article
- Spatiotemporal trends and geographic disparities in spatial accessibility to maternal and child health services in Nanning, China: impact of two-child policies.BMC health services research · 2024Article
- The dyadic associations among self-efficacy, dyadic coping, and health-related quality of life between high-risk pregnant women and spouses: a cross-sectional study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- The possible impact of the universal two-child policy on pregnancy outcomes.Archives of gynecology and obstetrics · 2024Article
- Perceptions of Chinese women with a history of gestational diabetes regarding health behaviors and related factors: a directed qualitative content analysis.BMC public health · 2024Article
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9 authors at 6 institutions in 3 countries.
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Abstract
The universal two-child policy (TCP; 2016) in China has affected many aspects of maternal-neonatal health. A tertiary hospital-based retrospective study (2011-2019) was used to find the association of these policy changes with maternal age and pregnancy outcomes in women with AMA (≥ 35 years) in the Hubei Province, China. The proportion of neonatal births to women with AMA increased by 68.8% from 12.5% in the one-child policy (OCP) period to 21.1% in the universal TCP period [aOR 1.76 (95% CI: 1.60, 1.93)]. In the univariate analysis, the proportion of preterm births (29.4% to 24.1%), low birth weight (LBW) (20.9% to 15.9%), and hypertensive disorders of pregnancy (HDP) (11.5% to 9.2%) significantly (p < 0.05) decreased in women with AMA from the OCP period to universal TCP period. However, the proportion of intrauterine growth restriction (IUGR) (0.2% to 0.7%) and gestational diabetes mellitus (GDM) (1.7% to 15.6%) was significantly (p < 0.05) increased over the policy changes. After adjusting for confounding factors, only the risk of GDM increased [aOR 10.91 (95% CI: 6.05, 19.67)] in women with AMA from the OCP period to the universal TCP period. In conclusion, the risk of GDM increased in women with AMA from the OCP period to the universal TCP period.
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