Evidence map›Paper›PMID 35322674›Full record

ArticleJournal of the American Heart Association2022

Layered Plaque in Organic Lesions in Patients With Coronary Artery Spasm.

Takeshi Nishi, Teruyoshi Kume, Ryotaro Yamada, Hiroshi Okamoto, Satsohi Koto, Masahiro Yamashita, Masahiko Ueno, Kyo Kamisaka, Yoshitaka Sasahira, Ayano Enzan and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Review
  3. Coronary plaque healing: a safety net or a hazard indicator?Journal of thrombosis and thrombolysis · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Erosion-like plaque image during coronary vasospasm.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Article
  8. Article
  9. CVIT 2025 clinical expert consensus document on intravascular ultrasound.Cardiovascular intervention and therapeutics · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Takeshi NishiDepartment of Cardiology Kawasaki Medical School Kurashiki Japan.ORCID 0000-0002-5503-4692
Teruyoshi KumeDepartment of Cardiology Kawasaki Medical School Kurashiki Japan.
Ryotaro YamadaDepartment of Cardiology Kawasaki Medical School Kurashiki Japan.ORCID 0000-0002-5040-2185
Hiroshi OkamotoDepartment of Cardiology Kawasaki Medical School Kurashiki Japan.
Satsohi KotoDepartment of Cardiology Kawasaki Medical School Kurashiki Japan.
Masahiro YamashitaDepartment of Cardiology Kawasaki Medical School Kurashiki Japan.
Masahiko UenoDepartment of Cardiology Kawasaki Medical School Kurashiki Japan.
Kyo KamisakaDepartment of Cardiology Kawasaki Medical School Kurashiki Japan.
Yoshitaka SasahiraDepartment of Cardiology Kawasaki Medical School Kurashiki Japan.
Ayano EnzanDepartment of Cardiology Kawasaki Medical School Kurashiki Japan.
Yasuyuki SudoDepartment of Cardiology Kawasaki Medical School Kurashiki Japan.
Tomoko TamadaDepartment of Cardiology Kawasaki Medical School Kurashiki Japan.ORCID 0000-0003-3946-813X
Terumasa KoyamaDepartment of Cardiology Kawasaki Medical School Kurashiki Japan.
Koichiro ImaiDepartment of Cardiology Kawasaki Medical School Kurashiki Japan.
Yoji NeishiDepartment of Cardiology Kawasaki Medical School Kurashiki Japan.
Shiro UemuraDepartment of Cardiology Kawasaki Medical School Kurashiki Japan.ORCID 0000-0002-6089-5358
Kawasaki Medical School · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Coronary artery spasm plays a vital role in the pathogenesis of coronary plaques. We sought to investigate the plaque characteristics of co-existing organic lesions in patients with coronary artery spasm in comparison to those without coronary artery spasm by intracoronary optical coherence tomography (OCT). Methods and Results We included 39 patients who presented with a symptom suspected of coronary spastic angina and had an organic lesion, defined as ≥plaque burden of 50% assessed by OCT. Coronary artery spasm was diagnosed by positive acetylcholine provocation test, or by spontaneous spasm detected during coronary angiography. A total of 51 vessels with an organic lesion were identified. Of these, coronary artery spasm was observed in 30 vessels (spasm), while not in 21 vessels (non-spasm). Organic lesions in the spasm vessels, compared with those in the non-spasm vessels, had a higher prevalence of layered plaque (93% versus 38%,

Indexed as

Coronary Artery DiseaseCoronary VasospasmPlaque, AtheroscleroticCoronary AngiographyCoronary VesselsHumansSpasmTomography, Optical Coherencecoronary artery spasmhealed plaquelayered plaqueoptical coherence tomography

Identifiers

PMID35322674
PMCPMC9075431
OpenAlexW4220816326

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.