Evidence map›Paper›PMID 35322669›Full record

ArticleJournal of the American Heart Association2022

PSG7 and 9 (Pregnancy-Specific β-1 Glycoproteins 7 and 9): Novel Biomarkers for Preeclampsia.

Manju Kandel, Teresa M MacDonald, Susan P Walker, Catherine Cluver, Lina Bergman, Jenny Myers, Roxanne Hastie, Emerson Keenan, Natalie J Hannan, Ping Cannon and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 4 countries.

Manju KandelTranslational Obstetrics Group Mercy Hospital for Women Heidelberg Victoria Australia.ORCID 0000-0003-1317-5232
Teresa M MacDonaldDepartment of Obstetrics and Gynaecology Mercy Hospital for Women University of Melbourne Heidelberg Victoria Australia.ORCID 0000-0001-9099-7745
Susan P WalkerDepartment of Obstetrics and Gynaecology Mercy Hospital for Women University of Melbourne Heidelberg Victoria Australia.
Catherine CluverTranslational Obstetrics Group Mercy Hospital for Women Heidelberg Victoria Australia.ORCID 0000-0002-0406-8964
Lina BergmanDepartment of Obstetrics and Gynecology Stellenbosch University Cape Town South Africa.ORCID 0000-0001-5202-9428
Jenny MyersDivision of Developmental Biology and Medicine University of ManchesterManchester Academic Health Science CentreSt Mary's Hospital Manchester United Kingdom.ORCID 0000-0003-0913-2096
Roxanne HastieTranslational Obstetrics Group Mercy Hospital for Women Heidelberg Victoria Australia.ORCID 0000-0002-4342-1943
Emerson KeenanDepartment of Obstetrics and Gynaecology Mercy Hospital for Women University of Melbourne Heidelberg Victoria Australia.ORCID 0000-0003-1966-2293
Natalie J HannanTranslational Obstetrics Group Mercy Hospital for Women Heidelberg Victoria Australia.
Ping CannonTranslational Obstetrics Group Mercy Hospital for Women Heidelberg Victoria Australia.
Tuong-Vi NguyenTranslational Obstetrics Group Mercy Hospital for Women Heidelberg Victoria Australia.
Natasha PritchardTranslational Obstetrics Group Mercy Hospital for Women Heidelberg Victoria Australia.
Stephen TongTranslational Obstetrics Group Mercy Hospital for Women Heidelberg Victoria Australia.
Tu'uhevaha J Kaitu'u-LinoTranslational Obstetrics Group Mercy Hospital for Women Heidelberg Victoria Australia.ORCID 0000-0001-6233-9737
The University of Melbourne · AUManchester Academic Health Science Centre · GBStellenbosch University · ZAUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Preeclampsia is pregnancy specific, involving significant maternal endothelial dysfunction. Predictive biomarkers are lacking. We evaluated the biomarker potential, expression, and function of PSG7 (pregnancy-specific β-1 glycoprotein 7) and PSG9 (pregnancy-specific β-1 glycoprotein 9) in preeclampsia. Methods and Results At 36 weeks gestation preceding term preeclampsia diagnosis, PSG7 and PSG9 (in Australian cohorts of n=918 and n=979, respectively) were significantly increased before the onset of term preeclampsia (PSG7,

Indexed as

Pre-EclampsiaPregnancy-Specific beta 1-GlycoproteinsAustraliaBiomarkersEndothelial CellsFemaleGlycoproteinsHumansPlacentaPlacenta Growth FactorPregnancyBiomarkersGlycoproteinsPlacenta Growth Factorpregnancy-specific beta-1-glycoprotein 7Pregnancy-Specific beta 1-Glycoproteinsbiomarkersplacentapreeclampsiapregnancypregnancy specific beta‐1 glycoproteins

Identifiers

PMID35322669
PMCPMC9075453
OpenAlexW4220777726

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.