Evidence map›Paper›PMID 35322526›Full record

ArticleJournal of applied clinical medical physics2022

End to end comparison of surface-guided imaging versus stereoscopic X-rays for the SRS treatment of multiple metastases with a single isocenter using 3D anthropomorphic gel phantoms.

Victoria Bry, Daniel Saenz, Evangelos Pappas, Georgios Kalaitzakis, Nikos Papanikolaou, Karl Rasmussen

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

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  14. HyperArcGels (Basel, Switzerland) · 2022
    Article
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  16. Article
  17. Validation of CatalystIn vivo (Athens, Greece)
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Victoria BryDepartment of Radiation Oncology, The University of Texas Health at San Antonio, San Antonio, Texas, USA.
Daniel SaenzDepartment of Radiation Oncology, The University of Texas Health at San Antonio, San Antonio, Texas, USA.
Evangelos PappasDepartment of Biomedical Sciences, Radiology and Radiotherapy Sector, University of West Attica, Athens, Greece.
Georgios KalaitzakisDepartment of Medical Physics, University of Crete, Heraklion, Greece.
Nikos PapanikolaouDepartment of Radiation Oncology, The University of Texas Health at San Antonio, San Antonio, Texas, USA.
Karl RasmussenDepartment of Radiation Oncology, The University of Texas Health at San Antonio, San Antonio, Texas, USA.
The University of Texas at San Antonio · USThe University of Texas Health Science Center at San Antonio · USUniversity of Crete · GRUniversity of West Attica · GR

Funding

NRSA Training Core (TL1)TL1TR002647 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHUN, YONG-HEE PATRICIA, FREI, CHRISTOPHER R. · 2018 to 2022
$1.8M
NCATS NIH HHS TL1 TR002647NIH HHS TL1TR002647
6 · The paper itself

Abstract

introductionTwo end-to-end tests evaluate the accuracy of a surface-guided radiation therapy (SGRT) system (CRAD Catalyst HD) for position verification in comparison to a stereoscopic x-ray imaging system (Brainlab Exactrac ) for single-isocenter, multiple metastases stereotactic radiosurgery (SRS) using 3D polymer gel inserts. MATERIALS AND

methodsA 3D-printed phantom (Prime phantom, RTsafe PC, Athens, Greece) with two separate cylindrical polymer gel inserts were immobilized in open-face masks and treated with a single isocentric, multitarget SRS plan. Planning was done in Brainlab (Elements) to treat five metastatic lesions in one fraction, and initial setup was done using cone beam computed tomography. Positional verification was done using orthogonal X-ray imaging (Brainlab Exactrac) and/or a surface imaging system (CRAD Catalyst HD, Uppsala, Sweden), and shift discrepancies were recorded for each couch angle. Forty-two hours after irradiation, the gel phantom was scanned in a 1.5 Tesla MRI, and images were fused with the patient computed tomography data/structure set for further analysis of spatial dose distribution.

resultsDiscrepancies between the CRAD Catalyst HD system and Brainlab Exactrac were <1 mm in the translational direction and <0.5° in the angular direction at noncoplanar couch angles. Dose parameters (D

conclusionDose metrics for a setup with surface imaging was found to be consistent with setup using x-ray imaging, demonstrating high accuracy and reproducibility for treatment delivery. Results indicate the feasibility of using surface imaging for position verification at noncoplanar couch angles for single-isocenter, multiple-target SRS using end-to-end quality assurance (QA) testing with 3D polymer gel dosimetry.

Indexed as

RadiosurgeryHumansPhantoms, ImagingPolymersRadiotherapy Planning, Computer-AssistedReproducibility of ResultsX-RaysPolymersC-RAD Catalyst HDend to endimmobilizationopen face masksQuality AssuranceSGRTSRSstereotactic radiosurgerysurface imaging

Identifiers

PMID35322526
PMCPMC9121024
OpenAlexW4220679134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.