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ArticleJournal of prosthodontics : official journal of the American College of Prosthodontists2022

Nutritional Assessment of Denture Wearers Using Matched Electronic Dental-Health Record Data.

Grace Gomez Felix Gomez, Sopanis D Cho, Roshan Varghese, Divya Rajendran, George J Eckert, Sruthi Surya Bhamidipalli, Theresa Gonzalez, Babar Ali Khan, Thankam Paul Thyvalikakath

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In one paragraph

Article in Journal of prosthodontics : official journal of the American College of Prosthodontists, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Grace Gomez Felix GomezDepartment of Cariology, Operative Dentistry & Dental Public Health, Indiana University School of Dentistry, Indianapolis, IN.ORCID https://orcid.org/0000-0001-8729-2277
Sopanis D ChoDepartment of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, IN.
Roshan VargheseGlaxoSmithKline Consumer Healthcare, Weybridge, United Kingdom.ORCID https://orcid.org/0000-0003-4749-0361
Divya RajendranDepartment of Cariology, Operative Dentistry & Dental Public Health, Indiana University School of Dentistry, Indianapolis, IN.
George J EckertDepartment of Biostatistics and Health Data Sciences, Indiana University School of Medicine, Indianapolis, IN.ORCID https://orcid.org/0000-0001-7798-7155
Sruthi Surya BhamidipalliDepartment of Biostatistics and Health Data Sciences, Indiana University School of Medicine, Indianapolis, IN.
Theresa GonzalezDepartment of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, IN.
Babar Ali KhanDepartment of Pulmonary & Critical Care, Indiana University School of Medicine, Indianapolis, IN.
Thankam Paul ThyvalikakathDepartment of Cariology, Operative Dentistry & Dental Public Health, Indiana University School of Dentistry, Indianapolis, IN.ORCID https://orcid.org/0000-0002-7294-2318
Indiana University Health · USIndiana University – Purdue University Indianapolis · USRegenstrief Institute · USAssociates in Neurology · USGlaxoSmithKline (United Kingdom) · GBIndiana University School of Medicine

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the nutritional profile of denture wearers through a retrospective cohort study using nutritional biomarkers from matched electronic dental and health record (EDR-EHR) data. MATERIALS AND

methodsThe case group (denture wearers) included matched EDR-EHR data of patients who received removable partial, complete, and implant-supported prosthodontic treatments between January 1, 2010 and December 31, 2018, study time. The control (nondenture wearers) group did not have recorded denture treatments and included patient records within 1 year of the denture index date (first date of case patients' receiving complete or partial denture) of the matching cases. The qualified patients' EDR were matched with their EHR based on the availability of laboratory reports within 2 years of receiving the dentures (index date). Nutritional biomarkers were selected from laboratory reports for complete blood count, comprehensive and basic metabolic profile, lipid, and thyroid panels. Summary statistics were performed, and general linear mixed effect models were used to evaluate the rate of change over time (slope) of nutritional biomarkers before and after the index date. Likelihood ratio tests were performed to determine the differences between dentures and controls.

resultsThe final cohort included 10,481 matched EDR-EHR data with 3,519 denture wearers and 6,962 controls that contained laboratory results within the study time. The denture wearers' mean age was 57 ±10 years and the control group was 56 ±10 years with 55% females in both groups. Pre-post analysis among denture wearers revealed decreased serum albumin (p = 0.002), calcium (p = 0.039), creatinine (p < 0.001) during the post-index time. Hemoglobin (Hb) was higher pre-index, and was decreasing during the time period but did not change post-index (p < 0.001). Among denture wearers, completely edentulous patients had a significant decrease in serum albumin, creatinine, blood urea nitrogen (BUN), but increased estimated glomerular filtration rate (eGFR). In partially edentulous patients, total cholesterol decreased (p = 0.018) and TSH (p = 0.004), BUN (p < 0.001) increased post-index. Patients edentulous in either upper or lower arch had decreased BUN and eGFR during post-index. Compared to controls, denture wearers showed decreased serum albumin and protein (p = 0.008), serum calcium (p = 0.001), and controls showed increased Hb (p = 0.035) during post-index.

conclusionsThe study results indicate nutritional biomarker variations among denture wearers suggesting a risk for undernutrition and the potential of using selected nutritional biomarkers to monitor nutritional profile.

Indexed as

Mouth, EdentulousNutrition AssessmentAgedCalciumCreatinineDenture, CompleteDenturesElectronicsFemaleHumansMaleMiddle AgedRetrospective StudiesSerum AlbuminCalciumCreatinineSerum Albumindata analyticsdental informaticsdietelectronic dental recordelectronic health recordmalnutritionnutritionolder adultsRemovable dentures

Identifiers

PMID35322481
PMCPMC9545162
OpenAlexW4220860737

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.