ReviewPain and therapy2022
EEG Recordings as Biomarkers of Pain Perception: Where Do We Stand and Where to Go?
Review in Pain and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The trial behind it
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Who cites it
31 citing papers in PubMed.
- Music therapy with adult burn patients in the intensive care unit: short-term analysis of electrophysiological signals during music-assisted relaxation.Scientific reports · 2024Trial
- Article
- Innovative strategies for diabetic peripheral neuropathy: From clinical management to emerging bioengineering solutions.Bioactive materials · 2026Review
- Displacement-Guided Focused Ultrasound of the Median Nerve Modulates Somatosensory Evoked Potentials in Humans.IEEE transactions on bio-medical engineering · 2026Article
- Pulsed Radiofrequency Analgesia Alters EEG Spatiotemporal Dynamics: A Microstate-Based Exploratory Study.Pain and therapy · 2026Article
- Preoperative Beta and Gamma EEG Spectral Power as Independent Predictors of Acute Postoperative Pain in Spinal Surgery: A Prospective Observational Cohort Study.Journal of pain research · 2026Article
- Quantitative electroencephalography as a next-generation tool in neurodiagnostics: significance, clinical applications, and practical interpretative frameworks.Frontiers in neuroscience · 2026Review
- Exploring Nociceptive-Analgesic Balance and EEG Modulation Patterns During General Anesthesia Using Holo-Hilbert Spectral Analysis.Pain research & management · 2026Article
- The moderating role of trait mindfulness on pain perception: insights from pain-related electroencephalography oscillations.Pain reports · 2025Article
- EEG power spectra encode both labour pain intensity and uterine contractions during the latent phase of labour.British journal of anaesthesia · 2025Article
- pBIC in analgesia management: sensitivity vs. specificity.Journal of anesthesia · 2025Article
- Pain classification using functional near infrared spectroscopy and assessment of virtual reality effects in cancer pain management.Scientific reports · 2025Article
- Is there a difference between heat-capsaicin induced low back pain and placebo for neural oscillations and inflammatory blood markers? An experimental randomized crossover study.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- A home-based EEG neurofeedback treatment for chronic neuropathic pain-a pilot study.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- EEG alpha/beta features as a biomarker for quantifying pain in patients with lumbar disk herniation.Frontiers in neuroscience · 2025Article
- Pain-Discriminating Information Decoded From Spatiotemporal Patterns of Hemodynamic Responses Measured by fMRI in the Human Brain.Human brain mapping · 2024Article
- Effect of music therapy on short-term psychological and physiological outcomes in mechanically ventilated patients: A randomized clinical pilot study.Journal of intensive medicine · 2024Article
- A Scoping Review of the Effect of EEG Neurofeedback on Pain Complaints in Adults with Chronic Pain.Journal of clinical medicine · 2024Article
- Measurements of pupillary unrest using infrared pupillometry fail to detect changes in pain intensity in patients after surgery: a prospective observational study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024Observational
- A novel theta-controlled vibrotactile brain-computer interface to treat chronic pain: a pilot study.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe universality and complexity of pain, which is highly prevalent, yield its significance to both patients and researchers. Developing a non-invasive tool that can objectively measure pain is of the utmost importance for clinical and research purposes. Traditionally electroencephalography (EEG) has been mostly used in epilepsy; however, over the recent years EEG has become an important non-invasive clinical tool that has helped increase our understanding of brain network complexities and for the identification of areas of dysfunction. This review aimed to investigate the role of EEG recordings as potential biomarkers of pain perception.
methodsA systematic search of the PubMed database led to the identification of 938 papers, of which 919 were excluded as a result of not meeting the eligibility criteria, and one article was identified through screening of the reference lists of the 19 eligible studies. Ultimately, 20 papers were included in this systematic review.
resultsChanges of the cortical activation have potential, though the described changes are not always consistent. The most consistent finding is the increase in the delta and gamma power activity. Only a limited number of studies have looked into brain networks encoding pain perception.
conclusionAlthough no robust EEG biomarkers of pain perception have been identified yet, EEG has potential and future research should be attempted. Designing strong research protocols, controlling for potential risk of biases, as well as investigating brain networks rather than isolated cortical changes will be crucial in this attempt.
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