ArticleInflammopharmacology2022
In vitro biological potential of the essential oil of some aromatic species used in Iranian traditional medicine.
Article in Inflammopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 26 citations in OpenAlex.
- GC-MS characterization and in vitro antimicrobial activity of essential oils from selected Lamiaceae species collected in Kashan, Iran.BMC plant biology · 2026Article
- Comparison of some biological activities of essential oils and extracts (waste and non-waste) of two species used by people: Salvia macrosiphon Boiss. and Salvia reuteriana Boiss. from natural habitats of Kashan.BMC plant biology · 2026Article
- Essential oil and extract of clevenger's waste of hymenocrater calycinus (boiss.) benth. as a non-toxicity option for cutaneous burns according to traditional use.Scientific reports · 2026Article
- Plant Essential Oils and Chronic Inflammatory Diseases: A Panoramic View of Molecular Mechanisms.Drug design, development and therapy · 2026Review
- Preservation of essential oil quality in endangered Ziziphora tenuior L. under different storage conditions.Scientific reports · 2025Article
- Integrated Network Pharmacology and Molecular Dynamics Reveal Multi-Target Anticancer Mechanisms ofPharmaceuticals (Basel, Switzerland) · 2025Article
- Potential Natural Blend Hydrosol TGLON Suppresses the Proliferation of Five Cancer Cell Lines and Also Ameliorates Idiopathic Pulmonary Fibrosis in a Mouse Model.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Chemical Profiling, Antioxidant and Antimicrobial Activities, and In Silico Evaluation ofPlants (Basel, Switzerland) · 2025Article
- Chemical composition and antimicrobial activity of a newly identified chemotype of Achillea wilhelmsii K.Koch from Kashan, Iran.Scientific reports · 2024Article
- Evaluation of Yield, Chemical Profile, and Antimicrobial Activity of Teucrium polium L. Essential Oil Used in Iranian Folk Medicine.Applied biochemistry and biotechnology · 2024Article
- Is Camphor the Future in Supporting Therapy for Skin Infections?Pharmaceuticals (Basel, Switzerland) · 2024Review
- Comparative Cytotoxicity of Menthol and Eucalyptol: An In Vitro Study on Human Gingival Fibroblasts.Pharmaceutics · 2024Article
- Article
- Evaluation of the composition and antimicrobial activities of essential oils from four species of Lamiaceae Martinov native to Iran.Scientific reports · 2022Article
- Article
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1 author at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The goal of this study is to evaluate the chemical compounds, the anti-bacterial/fungal activity, and the cytotoxicity of the essential oil of three species of lamiaceae in Iran. After the extraction of the essential oil implementing the hydrodistillation method, the analysis and identification of the compounds were carried out with a chromatograph coupled with a mass spectrometer. For the evaluation of the anti-bacterial/fungal activity of the essential oils, the measurement of the diameter of inhibition halo, the minimum inhibitory concentration (MIC), bactericidal and fungicidal concentrations (MBC/MFC) were utilized; and for the evaluation of the cytotoxic activity of the essential oils, the 3-(4,5-dimethylthiazolyl)-2,5-diphenyltetrazolium bromide (MTT) method was used. The results show that the dominant compounds in the Perovskia abrotanoides Kar essential oil were camphor (21.68%), 1,8-cineole (14.26%), and α-pinene (7.23%); moreover, the dominant compounds in the Salvia reuteriana Boiss. Essential oil were benzyl benzoate (27.10%), linalool (13.27%), and sclareol (7.75%); in addition, the dominant compounds in the Ziziphora clinopodioides subsp. rigida (Boiss.) Rech.f. were cyclofenchene (25.29%), pulegone (14.14%), and menthol (7.70%). The largest halo diameter of inhibition halo (~ 22 mm) was against Streptococcus pyogenes and the strongest inhibiting and killing activity was against Candida albicans (MIC and MFC = 125 μg/mL) shown by the S. reuteriana essential oil which, respectively, matched the control antibiotics rifampin and nystatin. The analysis of the MTT test results showed that the Z. clinopodioides subsp. rigida essential oil (with IC50 value of ~ 144.2500) had the strongest cytotoxic activity against human ovarian cancer cells (OVCAR-3). On the whole, the results show that the essential oil of the Lamiaceae family plants is a source for various compounds with potential biological activities which can serve as a possible alternative to produce herbal medicine which are effective on some microorganisms and cancer cell lines.
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