Evidence map›Paper›PMID 35322093›Full record

ArticleScientific reports2022

Altered proteome in translation initiation fidelity defective eIF5

Anup Kumar Ram, Monalisha Mallik, R Rajendra Reddy, Amol Ratnakar Suryawanshi, Pankaj V Alone

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Anup Kumar RamSchool of Biological Sciences, National Institute of Science Education and Research Bhubaneswar, P.O Jatni, Khurda, 752050, India.
Monalisha MallikSchool of Biological Sciences, National Institute of Science Education and Research Bhubaneswar, P.O Jatni, Khurda, 752050, India.
R Rajendra ReddyClinical Proteomics, DBT-Institute of Life Sciences, Bhubaneswar, Odisha, 751023, India.
Amol Ratnakar SuryawanshiClinical Proteomics, DBT-Institute of Life Sciences, Bhubaneswar, Odisha, 751023, India.
Pankaj V AloneSchool of Biological Sciences, National Institute of Science Education and Research Bhubaneswar, P.O Jatni, Khurda, 752050, India. pankaj@niser.ac.in.
Institute of Life Sciences · INNational Institute of Science Education and Research · INHomi Bhabha National Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recognition of the AUG start codon and selection of an open reading frame (ORF) is fundamental to protein biosynthesis. Defect in the fidelity of start codon selection adversely affect proteome and have a pleiotropic effect on cellular function. Using proteomic techniques, we identified differential protein abundance in the translation initiation fidelity defective eIF5

Indexed as

ProteomeProteomicsCodonCodon, InitiatorDNA DamageHydrogen PeroxideOxidative StressPeptide Initiation FactorsProtein BiosynthesisCodonCodon, InitiatorHydrogen PeroxidePeptide Initiation FactorsProteome

Identifiers

PMID35322093
PMCPMC8943034
OpenAlexW4220714284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.