Trial reportNutrition & diabetes2022
No obesity paradox in patients with community-acquired pneumonia - secondary analysis of a randomized controlled trial.
Trial report in Nutrition & diabetes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00973154 (Corticosteroid Treatment for Community-Acquired Pneumonia A Randomized, Double-blind Study- The STEP Trial), which is not on this map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Corticosteroid Treatment for Community-Acquired Pneumonia A Randomized, Double-blind Study- The STEP Trial
Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- Association between body mass index and the prognosis of community-acquired pneumonia in patients with nontuberculous mycobacterial pulmonary disease: a retrospective cohort study using a nationwide inpatient database.BMC infectious diseases · 2025Article
- Association of obesity on short- and long-term survival in patients with moderate to severe pneumonia-related ARDS: a retrospective cohort study.BMC pulmonary medicine · 2025Article
- Obesity paradox in patients with community-acquired pneumonia: Have you fully considered the confounding factors?World journal of clinical cases · 2025Article
- The obesity paradox and 90 day mortality in chronic critically ill patients: a cohort study using a large clinical database.European journal of medical research · 2024Article
- Impact of lower-respiratory tract infections on healthcare utilization and mortality in older adults: a Swedish population-based cohort study.Aging clinical and experimental research · 2024Article
- Obesity Paradox in Lung Diseases: What Explains It?Obesity facts · 2023Review
- The Impact of Nonalcoholic Fatty Liver Disease on Severe Community-Acquired Pneumonia Outcomes.Life (Basel, Switzerland) · 2022Article
- Article
- Effect of Undernutrition and Obesity on Clinical Outcomes in Adults with Community-Acquired Pneumonia.Nutrients · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity is associated with an increased risk for several chronic conditions and mortality. However, there are data in support of beneficial outcome in acute medical conditions such as community-acquired pneumonia (CAP), termed "obesity paradox". The aim of this study was to test the association of BMI with clinical outcomes in a large randomized clinical trial of patients hospitalized with CAP. DESIGN AND
methodsIn total, 773 patients hospitalized with CAP were included in this study. Patients were stratified into four groups according to their baseline BMI (underweight <18.5, normal weight 18.5-25, overweight 25-30, and obese >30 kg/m
resultsBMI and TTCS had a U-shaped association with shortest TTCS among patients at an overweight BMI of 28 kg/m
conclusionsThe overweight BMI group had shortest time to clinical stability. While underweight patients face adverse clinical outcomes, there is neither beneficial, nor adverse outcome in patients with obesity hospitalized for CAP. CLINICALTRIALS: gov (registration no. NCT00973154).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.