Evidence map›Paper›PMID 35321686›Full record

ArticleBMC neurology2022

Nomogram to predict 3-month unfavorable outcome after thrombectomy for stroke.

Xiao-Guang Zhang, Jia-Hui Wang, Wen-Hao Yang, Xiao-Qiong Zhu, Jie Xue, Zhi-Zhang Li, Yu-Ming Kong, Liang Hu, Shan-Shan Jiang, Xu-Shen Xu and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xiao-Guang Zhang *Department of Neurology, Yangpu Hospital, School of Medicine, Tongji University, 200092, Shanghai, China.
Jia-Hui Wang *Department of Neurology, Yangpu Hospital, School of Medicine, Tongji University, 200092, Shanghai, China.
Wen-Hao Yang *Department of Neurology, Yangpu Hospital, School of Medicine, Tongji University, 200092, Shanghai, China.
Xiao-Qiong ZhuDepartment of Neurology, Yangpu Hospital, School of Medicine, Tongji University, 200092, Shanghai, China.
Jie XueDepartment of Neurology, Yangpu Hospital, School of Medicine, Tongji University, 200092, Shanghai, China.
Zhi-Zhang LiDepartment of Neurology, Yangpu Hospital, School of Medicine, Tongji University, 200092, Shanghai, China.
Yu-Ming KongDepartment of Neurology, Yangpu Hospital, School of Medicine, Tongji University, 200092, Shanghai, China.
Liang HuDepartment of Neurology, Yangpu Hospital, School of Medicine, Tongji University, 200092, Shanghai, China.
Shan-Shan JiangDepartment of Neurology, Yangpu Hospital, School of Medicine, Tongji University, 200092, Shanghai, China.
Xu-Shen XuDepartment of Neurology, Yangpu Hospital, School of Medicine, Tongji University, 200092, Shanghai, China. sen82903@163.com.
Yun-Hua YueDepartment of Neurology, Yangpu Hospital, School of Medicine, Tongji University, 200092, Shanghai, China. Yunhua.Yue@tongji.edu.cn.ORCID http://orcid.org/0000-0002-5244-1954
Yangpu Hospital of Tongji University · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMechanical thrombectomy (MT) is an effective treatment for large-vessel occlusion in acute ischemic stroke, however, only some revascularized patients have a good prognosis. For stroke patients undergoing MT, predicting the risk of unfavorable outcomes and adjusting the treatment strategies accordingly can greatly improve prognosis. Therefore, we aimed to develop and validate a nomogram that can predict 3-month unfavorable outcomes for individual stroke patient treated with MT.

methodsWe analyzed 258 patients with acute ischemic stroke who underwent MT from January 2018 to February 2021. The primary outcome was a 3-month unfavorable outcome, assessed using the modified Rankin Scale (mRS), 3-6. A nomogram was generated based on a multivariable logistic model. We used the area under the receiver-operating characteristic curve to evaluate the discriminative performance and used the calibration curve and Spiegelhalter's Z-test to assess the calibration performance of the risk prediction model.

resultsIn our visual nomogram, gender (odds ratio [OR], 3.40; 95%CI, 1.54-7.54), collateral circulation (OR, 0.46; 95%CI, 0.28-0.76), postoperative mTICI (OR, 0.06; 95%CI, 0.01-0.50), stroke-associated pneumonia (OR, 5.76; 95%CI, 2.79-11.87), preoperative Na (OR, 0.82; 95%CI, 0.72-0.92) and creatinine (OR, 1.02; 95%CI, 1.01-1.03) remained independent predictors of 3-month unfavorable outcomes in stroke patients treated with MT. The area under the nomogram curve was 0.8791 with good calibration performance (P = 0.873 for the Spiegelhalter's Z-test).

conclusionsA novel nomogram consisting of gender, collateral circulation, postoperative mTICI, stroke-associated pneumonia, preoperative Na and creatinine can predict the 3-month unfavorable outcomes in stroke patients treated with MT.

Indexed as

Ischemic StrokeStrokeHumansNomogramsThrombectomyTreatment OutcomeMechanical ThrombectomyNomogramPredictionStrokeUnfavorable outcome

Identifiers

PMID35321686
PMCPMC8941794
OpenAlexW4220974951

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.