Evidence map›Paper›PMID 35321627›Full record

ArticleHuman vaccines & immunotherapeutics2022

mRNA vaccine-a desirable therapeutic strategy for surmounting COVID-19 pandemic.

Peixian Chen, Xiaoye Shi, Weixin He, Guowei Zhong, Yan Tang, Hailin Wang, Peidong Zhang

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peixian ChenZhujiang Hospital, Southern Medical University/The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, People's Republic of China.
Xiaoye ShiZhujiang Hospital, Southern Medical University/The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, People's Republic of China.
Weixin HeNanfang Hospital, Southern Medical University/The First School of Clinical Medicine, Southern Medical University, No, Guangzhou, Guangdong, People's Republic of China.
Guowei ZhongSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, People's Republic of China.
Yan TangZhujiang Hospital, Southern Medical University/The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, People's Republic of China.
Hailin WangDepartment of Cardiology, Heart Center, People's Hospital of Guangning County, Zhaoqing City, Guangdong, People's Republic of China.
Peidong ZhangDepartment of Cardiology, Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, People's Republic of China.ORCID 0000-0003-3243-691X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As an acute respiratory infectious disease, COVID-19 threatens the safety of global public health. Given the current lack of specific treatment against this disease, research and development of vaccines have become sharp weapons for overcoming the pandemic. mRNA vaccines have become the lead in COVID-19 vaccination strategies due to their advantages, such as rapid industrial production and efficacy. A total of 137 COVID-19 vaccines have entered the clinical trial stage, among which 23 are mRNA vaccines, accounting for 17% of the total vaccines. Herein, we summarize the research and developmental processes of mRNA vaccines as well as the approach for protecting the human body against infection. Focusing on the latest clinical trial data of two COVID-19 mRNA vaccines from Pfizer and Modena, we discuss their effectiveness and safety. Finally, we analyze the challenges and problems that mRNA vaccines face in controlling the COVID-19 pandemic.

Indexed as

COVID-19Influenza, HumanInfluenza VaccinesCOVID-19 VaccinesHumansmRNA VaccinesPandemicsVaccines, SyntheticCOVID-19 VaccinesInfluenza VaccinesmRNA VaccinesVaccines, Syntheticclinical trialCOVID-19immune responsesinfectious diseasesmRNA vaccinesSARS-CoV-2

Identifiers

PMID35321627
PMCPMC8973374

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.