Evidence map›Paper›PMID 35321507›Full record

ArticleFrontiers in neurology2022

Early Neurological Improvement Predicts Clinical Outcome After Thrombectomy for Distal Medium Vessel Occlusions.

Maud Wang, Yousra Farouki, Franny Hulscher, Benjamin Mine, Thomas Bonnet, Stephanie Elens, Juan Vazquez Suarez, Lise Jodaitis, Noémie Ligot, Gilles Naeije and 2 more

Abstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Maud WangDepartment of Interventional Neuroradiology, Erasme University Hospital, Brussels, Belgium.
Yousra FaroukiDepartment of Interventional Neuroradiology, Erasme University Hospital, Brussels, Belgium.
Franny HulscherDepartment of Interventional Neuroradiology, Erasme University Hospital, Brussels, Belgium.
Benjamin MineDepartment of Interventional Neuroradiology, Erasme University Hospital, Brussels, Belgium.
Thomas BonnetDepartment of Interventional Neuroradiology, Erasme University Hospital, Brussels, Belgium.
Stephanie ElensDepartment of Interventional Neuroradiology, Erasme University Hospital, Brussels, Belgium.
Juan Vazquez SuarezDepartment of Interventional Neuroradiology, Erasme University Hospital, Brussels, Belgium.
Lise JodaitisDepartment of Neurology, Erasme University Hospital, Brussels, Belgium.
Noémie LigotDepartment of Neurology, Erasme University Hospital, Brussels, Belgium.
Gilles NaeijeDepartment of Neurology, Erasme University Hospital, Brussels, Belgium.
Boris LubiczDepartment of Interventional Neuroradiology, Erasme University Hospital, Brussels, Belgium.
Adrien GuenegoDepartment of Interventional Neuroradiology, Erasme University Hospital, Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Purpose: Good clinical outcome predictors have been established in mechanical thrombectomy (MT) for acute ischemic stroke (AIS) caused by large vessel occlusion (LVO). An early neurological improvement (ENI), defined as a reduction of ≥8 on the National Institutes of Health Stroke Scale (NIHSS), compared with the baseline score or an NIHSS of 0 or 1 at 24 h after MT, is a strong predictor of favorable outcome. We aimed to study the impact of ENI after MT for distal medium vessel occlusions (DMVO). Methods: We retrospectively analyzed the data of consecutive patients who underwent MT for a primary DMVO in one large academic center. We compared clinical outcomes between patients with DMVO stratified by ENI. Multivariate analyses were performed to determine the impact of ENI on good 90-day outcome (modified Rankin scale of 0-2) and identify factors contributing to ENI. Results: Between January 2018 and January 2021, 61 patients underwent an MT for an AIS with a primary DMVO. An ENI was seen in 24 (39%) patients (ENI+). Outcomes were significantly better in ENI+ patients, with 83% achieving a good outcome at 3 months vs. 43% for patients without ENI (ENI-; Conclusion: ENI at day 1 following MT for DMVO stroke is a strong independent predictor of good to excellent 3-month clinical outcome.

Indexed as

distal thrombectomyendovascular recanalizationintravenous thrombolysispredictionstroke

Identifiers

PMID35321507
PMCPMC8936066

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.