Evidence map›Paper›PMID 35321327›Full record

ArticleFrontiers in pharmacology2022

Dehydrocostus Lactone Suppresses Dextran Sulfate Sodium-Induced Colitis by Targeting the IKKα/β-NF-κB and Keap1-Nrf2 Signalling Pathways.

Yun Yuan, Qiongying Hu, Lu Liu, Fan Xie, Luyao Yang, Yuchen Li, Chuantao Zhang, Hongqing Chen, Jianyuan Tang, Xiaofei Shen

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  7. Frontiers in pharmacology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yun YuanHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Qiongying HuDepartment of Laboratory Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Lu LiuCollege of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Fan XieHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Luyao YangHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yuchen LiHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Chuantao ZhangDepartment of Respiratory Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Hongqing ChenHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Jianyuan TangHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Xiaofei ShenHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dehydrocostus lactone (DCL) is a major sesquiterpene lactone isolated from

Indexed as

colitisdehydrocostus lactoneIKKα/β-NF-κB pathwayinflammationKeap1-Nrf2 pathwaymacrophages

Identifiers

PMID35321327
PMCPMC8936814

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.