ArticleFrontiers in human neuroscience2022
Past and Future Explanations for Depersonalization and Derealization Disorder: A Role for Predictive Coding.
Article in Frontiers in human neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Sensory Processing, Dissociation, and Affective Symptoms in Misophonia: A Cross-Sectional Study of 35 Adults.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Health-related quality of life related to diabetes multisensory deficits and derealization.Scientific reports · 2025Article
- It Is Movement All the Way Down: Broken Rhythms and Embodied Selfhood in Depersonalization.Behavioral sciences (Basel, Switzerland) · 2025Article
- Altered Self-Referential-Related Brain Regions in Depersonalization-Derealization Disorder.Brain and behavior · 2025Article
- Relationships between depersonalization-derealization symptoms and separation anxiety in adult patients with mood and anxiety disorders.Frontiers in psychiatry · 2025Article
- Self-disturbance in first-episode psychosis: Theoretical framework and potential cannabis interactions - a systematic review.Frontiers in psychiatry · 2025Review
- Unraveling the brain dynamics of Depersonalization-Derealization Disorder: a dynamic functional network connectivity analysis.BMC psychiatry · 2024Article
- Brain-heart interaction disruption in major depressive disorder: disturbed rhythm modulation of the cardiac cycle on brain transient theta bursts.European archives of psychiatry and clinical neuroscience · 2024Article
- The integrative process promoted by EMDR in dissociative disorders: neurobiological mechanisms, psychometric tools, and intervention efficacy on the psychological impact of the COVID-19 pandemic.Frontiers in psychology · 2023Review
- Depersonalization disorder as a systematic downregulation of interoceptive signals.Scientific reports · 2022Article
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Authors and funding
3 authors.
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Abstract
Depersonalization (DP) and derealization (DR) refer to states of dissociation in which one feels a sense of alienation in relation to one's self and environment, respectively. Whilst transient episodes often diminish without treatment, chronic experiences of DP and DR may last for years, with common treatments lacking a strong evidence base for their efficacy. We propose a theoretical explanation of DP and DR based on interoceptive predictive coding, and discuss how transient experiences of DP and DR may be induced in the non-clinical population using virtual reality. Further, we review the use of heartbeat evoked potentials in detecting the neural correlates of DP and DR allowing for an objective measure of these experiences in the non-clinical population. Finally, we discuss how the induction and detection of transient experiences of DP and DR in the non-clinical population could shed light on how the brain constructs one's sense of self and reality.
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