Evidence map›Paper›PMID 35321157›Full record

ArticleWorld journal of clinical cases2022

Relationship between treatment types and blood-brain barrier disruption in patients with acute ischemic stroke: Two case reports.

Youngbeom Seo, Jonghoon Kim, Min Cheol Chang, Hyungkyu Huh, Eun-Hee Lee

Abstract readCase Reports
In one paragraph

Article in World journal of clinical cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Blood-brain barrier breakdown in brain ischemia: Insights from MRI perfusion imaging.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Youngbeom SeoDepartment of Neurosurgery, College of Medicine, Yeungnam University, Daegu 42415, South Korea.
Jonghoon KimDepartment of Neurosurgery, College of Medicine, Yeungnam University, Daegu 42415, South Korea. kjhns@yu.ac.kr.
Min Cheol ChangDepartment of Rehabilitation Medicine, College of Medicine, Yeungnam University, Daegu 42415, South Korea.
Hyungkyu HuhMedical Interdisciplinary Team, Medical Device Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, South Korea.
Eun-Hee LeeMedical Interdisciplinary Team, Medical Device Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlood-brain barrier (BBB) disruption plays an important role in the development of neurological dysfunction in ischemic stroke. However, diagnostic modalities that can clearly diagnose the degree of BBB disruption in ischemic stroke are limited. Here, we describe two cases in which the usefulness of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in detecting BBB disruption was evaluated after treatment of acute ischemic stroke using two different methods. CASE SUMMARY: The two patients of similar age and relatively similar cerebral infarction locations were treated conservatively or with thrombectomy, although their sex was different. As a result of analysis by performing DCE-MRI, it was confirmed that BBB disruption was significantly less severe in the patient who underwent thrombectomy (

conclusionOur cases suggest that BBB disruption could be important if BBB permeability is used to guide clinical treatment.

Indexed as

Blood–brain barrierCase reportDynamic contrast-enhanced magnetic resonance imagingIschemic strokePenumbraThrombectomy

Identifiers

PMID35321157
PMCPMC8895168

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.