Evidence map›Paper›PMID 35321090›Full record

ArticlePharmacogenomics and personalized medicine2022

The Single Nucleotide Polymorphisms of AP1S1 are Associated with Risk of Esophageal Squamous Cell Carcinoma in Chinese Population.

Feng Su, Yong Fang, Jinjie Yu, Tian Jiang, Siyun Lin, Shaoyuan Zhang, Lu Lv, Tao Long, Huiwen Pan, Junqing Qi and 6 more

Abstract read
In one paragraph

Article in Pharmacogenomics and personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. IAPP blocks anti-breast cancer function of CD8Frontiers in immunology · 2024
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Feng Su *Department of Thoracic Surgery, Zhongshan Hospital of Fudan University, Shanghai, People's Republic of China.
Yong Fang *Department of Thoracic Surgery, Zhongshan Hospital of Fudan University, Shanghai, People's Republic of China.ORCID 0000-0003-1910-6465
Jinjie YuDepartment of Thoracic Surgery, Zhongshan Hospital of Fudan University, Shanghai, People's Republic of China.ORCID 0000-0002-0027-4007
Tian JiangDepartment of Thoracic Surgery, Zhongshan Hospital of Fudan University, Shanghai, People's Republic of China.
Siyun LinDepartment of Thoracic Surgery, Zhongshan Hospital of Fudan University, Shanghai, People's Republic of China.
Shaoyuan ZhangDepartment of Thoracic Surgery, Zhongshan Hospital of Fudan University, Shanghai, People's Republic of China.ORCID 0000-0002-6187-4313
Lu LvDepartment of Cardiothoracic Surgery, Affiliated People's Hospital of Jiangsu University, Jiangsu, People's Republic of China.
Tao LongDepartment of Cardiothoracic Surgery, Affiliated People's Hospital of Jiangsu University, Jiangsu, People's Republic of China.
Huiwen PanDepartment of Cardiothoracic Surgery, Affiliated People's Hospital of Jiangsu University, Jiangsu, People's Republic of China.
Junqing QiDepartment of Cardiothoracic Surgery, Affiliated People's Hospital of Jiangsu University, Jiangsu, People's Republic of China.
Qiang ZhouDepartment of Thoracic Surgery, Sichuan Cancer Hospital & Institute, Sichuan, People's Republic of China.
Weifeng TangDepartment of Cardiothoracic Surgery, Nanjing Drum Tower Hospital, Jiangsu, People's Republic of China.
Guowen DingDepartment of Cardiothoracic Surgery, Affiliated People's Hospital of Jiangsu University, Jiangsu, People's Republic of China.
Liming WangDepartment of Respiratory, Shanghai Xuhui Central Hospital, Shanghai, People's Republic of China.
Lijie TanDepartment of Thoracic Surgery, Zhongshan Hospital of Fudan University, Shanghai, People's Republic of China.
Jun YinDepartment of Thoracic Surgery, Zhongshan Hospital of Fudan University, Shanghai, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The σ1A subunit of the adaptor protein 1 (AP1S1) participates in various intracellular transport pathways, especially the maintenance of copper homeostasis, which is pivotal in carcinogenesis. It is therefore rational to presume that AP1S1 might also be involved in carcinogenesis. In this hospital-based case-control study, we investigated the genetic susceptibility to ESCC in relation to SNPs of Methods: A database containing a total of 1303 controls and 1043 ESCC patients were retrospectively studied. The Results: Conclusion:

Indexed as

AP1S1ESCCesophageal squamous cell carcinomasingle nucleotide polymorphismSNP

Identifiers

PMID35321090
PMCPMC8938157

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.