Evidence map›Paper›PMID 35321014›Full record

ArticleFrontiers in pediatrics2022

Case Report: Interest of Positron Emission Tomography in Pediatric Small Vessel Primary Angiitis of the Central Nervous System.

Morgane Belcour, Pauline Dontaine, Anne Monier, Laetitia Lebrun, Isabelle Salmon, Olivier De Witte, Serge Goldman, Xavier De Tiège, Alec Aeby

Abstract readCase Reports
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Morgane BelcourDepartment of Pediatrics, Hôpital des Enfants Reine Fabiola (HUDERF), Université Libre de Bruxelles (ULB), Brussels, Belgium.
Pauline DontaineDepartment of Pediatric Neurology, Université Libre de Bruxelles - Hôpital Universitaire Des Enfants Reine Fabiola (ULB-HUDERF), Brussels, Belgium.
Anne MonierDepartment of Pediatric Neurology, Université Libre de Bruxelles - Hôpital Universitaire Des Enfants Reine Fabiola (ULB-HUDERF), Brussels, Belgium.
Laetitia LebrunDepartment of Anatomopathology, Cliniques Universitaires de Bruxelles (CUB) Hôpital Erasme, Université Libre de Bruxelles (ULB), Brussels, Belgium.
Isabelle SalmonDepartment of Anatomopathology, Cliniques Universitaires de Bruxelles (CUB) Hôpital Erasme, Université Libre de Bruxelles (ULB), Brussels, Belgium.
Olivier De WitteDepartment of Neurosurgery, Cliniques Universitaires de Bruxelles (CUB) Hôpital Erasme, Université Libre de Bruxelles (ULB), Brussels, Belgium.
Serge GoldmanDepartment of Functional Neuroimaging, Service of Nuclear Medicine, Cliniques Universitaires de Bruxelles (CUB) Hôpital Erasme, Université Libre de Bruxelles (ULB), Brussels, Belgium.
Xavier De TiègeDepartment of Functional Neuroimaging, Service of Nuclear Medicine, Cliniques Universitaires de Bruxelles (CUB) Hôpital Erasme, Université Libre de Bruxelles (ULB), Brussels, Belgium.
Alec AebyDepartment of Pediatric Neurology, Université Libre de Bruxelles - Hôpital Universitaire Des Enfants Reine Fabiola (ULB-HUDERF), Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary angiitis of the central nervous system (PACNS) is a rare inflammatory disease affecting central nervous system vessels. The diagnosis, which requires confirmation by brain biopsy, remains challenging due to unspecific clinical presentation and low specificity of imaging and laboratory exams. In these two pediatric biopsy-proven cases of svPACNS we demonstrate that brain positron emission tomography (PET) show a high metabolic activity that extends beyond brain MRI abnormalities. Therefore, combining MRI and PET abnormalities to adequately guide brain biopsy might increase the diagnostic yield of this rare condition.

Indexed as

brain biopsycerebral vasculitismagnetic resonance imaging (MRI)positron emission tomography (PET)primary angiitis of central nervous system

Identifiers

PMID35321014
PMCPMC8935040

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.