Evidence map›Paper›PMID 35320936›Full record

ArticleFrontiers in immunology2022

Different Multivariable Risk Factors for Rapid Progressive Interstitial Lung Disease in Anti-MDA5 Positive Dermatomyositis and Anti-Synthetase Syndrome.

Yu Zuo, Lifang Ye, Fang Chen, Yawen Shen, Xin Lu, Guochun Wang, Xiaoming Shu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 4 pooled it
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 4 syntheses or guidelines pooled it, 79 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yu ZuoDepartment of Rheumatology, Key Laboratory of Myositis, China-Japan Friendship Hospital, Beijing, China.
Lifang YeDepartment of Rheumatology, Key Laboratory of Myositis, China-Japan Friendship Hospital, Beijing, China.
Fang ChenDepartment of Rheumatology, Key Laboratory of Myositis, China-Japan Friendship Hospital, Beijing, China.
Yawen ShenDepartment of Rheumatology, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Xin LuDepartment of Rheumatology, Key Laboratory of Myositis, China-Japan Friendship Hospital, Beijing, China.
Guochun WangDepartment of Rheumatology, Key Laboratory of Myositis, China-Japan Friendship Hospital, Beijing, China.
Xiaoming ShuDepartment of Rheumatology, Key Laboratory of Myositis, China-Japan Friendship Hospital, Beijing, China.
China-Japan Friendship Hospital · CNPeking Union Medical College Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Interstitial lung disease (ILD) is frequently observed in anti-melanoma differentiation-associated protein 5 (MDA5) antibody positive dermatomyositis (DM) and anti-synthetase syndrome (ASS), where they often develop a rapidly progressive ILD (RP-ILD) leading to poor prognosis. Objective: The aim of this study was to construct multivariable prediction risk factors for rapid progressive ILD (RP-ILD) in anti-MDA5 positive DM (MDA5 Methods: 333 idiopathic inflammatory myopathy (IIM) associated ILD patients were studied retrospectively. Risk factors for RP-ILD in MDA5 Results: RP-ILD was more prevalent in MDA5 Conclusions: There were significant different mortality and multivariable risk factors for RP-ILD in MDA5

Indexed as

DermatomyositisLung Diseases, InterstitialMyositisAutoantibodiesCarcinoembryonic AntigenDisease ProgressionFerritinsHumansInterferon-Induced Helicase, IFIH1LigasesRetrospective StudiesRisk FactorsSyndromeAutoantibodiesCarcinoembryonic AntigenFerritinsIFIH1 protein, humanInterferon-Induced Helicase, IFIH1Ligasesanti-MDA5 antibodyanti-synthetase syndromehyperferritinemiaidiopathic inflammatory myopathyrapidly progressive interstitial lung disease

Identifiers

PMID35320936
PMCPMC8936070
OpenAlexW4220689205

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.