ArticlePloS one2022
Persisting olfactory dysfunction in post-COVID-19 is associated with gustatory impairment: Results from chemosensitive testing eight months after the acute infection.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Stellate Ganglion Block for the Treatment of COVID-19-Induced Olfactory Dysfunction: A Prospective Pilot Study
Stellate Ganglion Block With Lidocaine for the Treatment of COVID-19-Induced Parosmia: Double-Blinded, Placebo-Controlled Randomized Clinical Trial
Stellate Ganglion Block for the Treatment of COVID-19-Induced Parosmia: Double-Blinded, Placebo-Controlled Randomized Clinical Trial
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Oral Manifestations in the Post COVID-19 Condition: A Systematic Review With Meta-Analysis.Reviews in medical virology · 2025Pooled it
- Effect of Long COVID-19: Self-Reported Questionnaires and Objective Olfactory and Gustatory Evaluations.Diseases (Basel, Switzerland) · 2026Article
- Evaluating methods for quantitative olfactory assessment: a comparative longitudinal analysis of Sniffin' Sticks and alternative tools.Chemical senses · 2026Article
- The role of the caudate nucleus in taste function: a comprehensive narrative review.Frontiers in neuroscience · 2026Review
- Granulocyte Colony Stimulating Factor (G-CSF) and Olfactory Function-A Clinical Pilot Study.Laryngoscope investigative otolaryngology · 2025Article
- Neuroimaging evaluations of olfactory, gustatory, and neurological deficits in patients with long-term sequelae of COVID-19.Brain imaging and behavior · 2024Article
- Long-term recovery of taste and smell following acute COVID-19 infection in a New Jersey cohort.Science talks · 2024Article
- Effect of oral zinc and steroids on long COVID hyposmia and hypogeusia.SAGE open medicine · 2024Article
- Using SCENTinel® to predict SARS-CoV-2 infection: insights from a community sample during dominance of Delta and Omicron variants.Frontiers in public health · 2024Article
- Remote psychophysical testing of smell in patients with persistent olfactory dysfunction after COVID-19.Scientific reports · 2023Article
- Long COVID: An approach to clinical assessment and management in primary care.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2023Article
- Long-term Consequences of COVID-19: Chemosensory Disorders.Current allergy and asthma reports · 2023Review
- COVID-19 Oral Sequelae: Persistent Gustatory and Saliva Secretory Dysfunctions after Recovery from COVID-19.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2023Review
- Dysphagia, dysphonia and olfactory disease: a map of Cochrane evidence relevant to rehabilitation for people with post COVID-19 condition.European journal of physical and rehabilitation medicine · 2022Review
- Author's reply to the Letter to the Editor "The study of olfactory dysfunction in SARS-CoV-2 variants".European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Article
- Topical Administration of Mometasone Is Not Helpful in Post-COVID-19 Olfactory Dysfunction.Life (Basel, Switzerland) · 2022Article
- Assessment of Smell and Taste Disturbances among COVID-19 Convalescent Patients: A Cross-Sectional Study in Armenia.Journal of clinical medicine · 2022Article
- Development of restrictive eating disorders in children and adolescents with long-COVID-associated smell and taste dysfunction.Frontiers in pediatrics · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Olfactory and gustatory disorders are prominent symptoms of acute COVID-19. Although both senses recover in many patients within weeks to months, persistency has been described in up to 60%. However up to now most reports on the course of chemosensitive disorders after COVID-19 are not based on psychophysical testing but only on subjective patients' ratings. In this study we assessed both olfaction and gustation using psychophysical tests eight months after COVID-19. Validated psychophysical testing revealed hyposmia in 18% and hypogeusia in even 32% of 303 included patients. This shows that olfactory and especially gustatory disorders have to be seen as important chronic symptoms post-COVID-19. The high prevalence of gustatory dysfunction indicates that gustatory function does not recover or might even deteriorate in the months following the acute infection.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.