ReviewJournal of assisted reproduction and genetics2022
Live birth from a blastocyst derived from a conjoined oocyte in a frozen embryo transfer cycle: a case report and a literature review.
Review in Journal of assisted reproduction and genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Multi-oocyte follicles in the bovine ovary: occurrence, activation, and growth during early in vitro folliculogenesis in a dynamic culture bioreactor.Journal of assisted reproduction and genetics · 2025Article
- The Istanbul consensus update: a revised ESHRE/ALPHA consensus on oocyte and embryo static and dynamic morphological assessment†,‡.Human reproduction (Oxford, England) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
The significance of conjoined oocytes in the clinical in vitro fertilization (IVF) laboratory setting has been questionable due to the extremely limited data available. This issue is discussed by presenting one case for conjoined oocyte observed in the program of the assisted reproduction and by including a review of corresponding literature. This report describes a successful clinical pregnancy with subsequent live birth from a conjoined oocyte. To our knowledge, there are only three reported cases of successful live birth from conjoined oocytes, but this is the first case of live birth from a blastocyst derived from a conjoined oocyte fertilized using intracytoplasmic sperm injection (ICSI) in a frozen embryo transfer cycle. Moreover, this study reports the first time that live birth of a conjoined oocyte is achieved without removing the degenerated immature oocyte prior to transfer. It demonstrates that the degenerated immature oocyte has no adverse effect on subsequent embryo development and pregnancy outcome. In addition, we reviewed the literature to evaluate the origin, incidence, safety, and significance of conjoined oocytes in reproductive health. We further confirm previous reports that demonstrate that a mature oocyte from conjoined-oocyte complexes can be fertilized by standard IVF or ICSI and lead to the development of a blastocyst, subsequent pregnancy, and live birth.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.