Evidence map›Paper›PMID 35320383›Full record

SynthesisClinical oral investigations2022

Clinical performance of resin-matrix ceramic partial coverage restorations: a systematic review.

Hanan Fathy, Hamdi H Hamama, Noha El-Wassefy, Salah H Mahmoud

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Clinical oral investigations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07648485 (Clinical Performance of CAD/CAM Hard Hybrid Ceramic Inlays Versus Resin Composite Inlays in Vital Molars With Extensive Occluso-Proximal Cavities), which is not on this map. Cited by 34 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07648485 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Clinical Performance of CAD/CAM Hard Hybrid Ceramic Inlays Versus Resin Composite Inlays in Vital Molars With Extensive Occluso-Proximal Cavities: Two-Year Randomized Clinical Trial

TypeinterventionalSponsorCairo UniversityRan2026 to 2028Enrolled50ConditionsDental Caries, Cavity, Dental, Proximal Dental CariesArmshybrid ceramics, Composite resin
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Restorative interventions and management of primary and permanent molars affected by molar incisor hypo-mineralization: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Pooled it
  2. Interdisciplinary Delphi study by PROSEC North America: Recommendations on single indirect restorations made from ceramic and nonmetallic biomaterials for posterior teeth.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025
    Pooled it
  3. Survival and Complications of Partial Coverage Restorations on Posterior Teeth-A Systematic Review and Meta-Analysis.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hanan FathyOperative Dentistry Department, Faculty of Dentistry, Mansoura University, Algomhoria St, Mansoura City, 35516, Egypt.
Hamdi H HamamaOperative Dentistry Department, Faculty of Dentistry, Mansoura University, Algomhoria St, Mansoura City, 35516, Egypt. hamdy@connect.hku.hk.ORCID http://orcid.org/0000-0003-3205-345X
Noha El-WassefyDental Biomaterials Science Dept, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
Salah H MahmoudOperative Dentistry Department, Faculty of Dentistry, Mansoura University, Algomhoria St, Mansoura City, 35516, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate clinical performance of the new CAD/CAM resin-matrix ceramics and compare it with ceramic partial coverage restorations. MATERIALS AND

methodsAn electronic search of 3 databases (The National Library of Medicine (MEDLINE/PubMed), Scopus, and the Cochrane Central Register of Controlled Trials) was conducted. English clinical studies published between 2005 and September 2020 that evaluated the clinical performance of CAD/CAM resin-matrix ceramics inlays, onlays, or overlays were selected. The primary clinical question was applied according to PICOS strategy (Population, Intervention, Comparison, Outcome, Study design). The included studies were individually evaluated for risk of bias according to the modified Cochrane Collaboration tool criteria.

resultsA total of 7 studies were included according to the established inclusion and exclusion criteria. From the included studies, 6 were randomized clinical trials while one study was longitudinal observational study without control group. According to the results of the included studies, the success rate of CAD/CAM resin-based composite ranged from 85.7 to 100% whereas the success rate reported for ceramic partial coverage restorations ranged from 93.3 to 100%. Fractures and debondings are found to be the most common cause of restorations failure.

conclusionCAD/CAM resin-based composite can be considered a reliable material for partial coverage restorations with clinical performance similar to glass ceramic restorations. However, this result needs to be confirmed in long-term evaluations. CLINICAL RELEVANCE: CAD/CAM resin-based composites provide a potential alternative to ceramic indirect restorations. However, clinicians must be aware of the lake of knowledge regarding long-term outcome.

Indexed as

CeramicsInlaysComposite ResinsComputer-Aided DesignDental MaterialsDental PorcelainLongitudinal StudiesObservational Studies as TopicComposite ResinsDental MaterialsDental PorcelainCAD/CAMCeramicsHybrid ceramicsIndirect restorationsResin-matrix ceramics

Identifiers

PMID35320383
PMCPMC9072524

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.