Evidence map›Paper›PMID 35320317›Full record

Trial reportPloS one2022

Factors associated with community acquired severe pneumonia among under five children in Dhaka, Bangladesh: A case control analysis.

Sabiha Nasrin, Md Tariqujjaman, Marufa Sultana, Rifat A Zaman, Shahjahan Ali, Mohammod J Chisti, Abu S G Faruque, Tahmeed Ahmed, George J Fuchs, Niklaus Gyr and 1 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

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  12. Identification ofThe Journal of international medical research · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Sabiha NasrinNutrition and Clinical Services Division, icddr,b, Dhaka, Bangladesh.ORCID 0000-0001-9618-7081
Md TariqujjamanNutrition and Clinical Services Division, icddr,b, Dhaka, Bangladesh.
Marufa SultanaNutrition and Clinical Services Division, icddr,b, Dhaka, Bangladesh.
Rifat A ZamanNutrition and Clinical Services Division, icddr,b, Dhaka, Bangladesh.
Shahjahan AliNutrition and Clinical Services Division, icddr,b, Dhaka, Bangladesh.
Mohammod J ChistiNutrition and Clinical Services Division, icddr,b, Dhaka, Bangladesh.
Abu S G FaruqueNutrition and Clinical Services Division, icddr,b, Dhaka, Bangladesh.ORCID 0000-0001-8343-4653
Tahmeed AhmedNutrition and Clinical Services Division, icddr,b, Dhaka, Bangladesh.
George J FuchsDepartment of Pediatrics, College of Medicine and Department of Epidemiology, College of Public Health, University of Kentucky, Lexington, Kentucky, United States of America.
Niklaus GyrFaculty of Medicine, University of Basel, Basel, Switzerland.
Nur H AlamNutrition and Clinical Services Division, icddr,b, Dhaka, Bangladesh.
International Centre for Diarrhoeal Disease Research · BDDeakin University · AUUniversity of Basel · CHUniversity of Kentucky · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPneumonia is the leading cause of death in children globally with the majority of these deaths observed in resource-limited settings. Globally, the annual incidence of clinical pneumonia in under-five children is approximately 152 million, mostly in the low- and middle-income countries. Of these, 8.7% progressed to severe pneumonia requiring hospitalization. However, data to predict children at the greatest risk to develop severe pneumonia from pneumonia are limited.

methodSecondary data analysis was performed after extracting relevant data from a prospective cluster randomized controlled clinical trial; children of either sex, aged two months to five years with pneumonia or severe pneumonia acquired in the community were enrolled over a period of three years in 16 clusters in urban Dhaka city.

resultsThe analysis comprised of 2,597 children aged 2-59 months. Of these, 904 and 1693 were categorized as pneumonia (controls) and severe pneumonia (cases), respectively based on WHO criteria. The median age of children was 9.2 months (inter quartile range, 5.1-17.1) and 1,576 (60%) were male. After adjustment for covariates, children with temperature ≥38°C, duration of illness ≥3 days, male sex, received prior medical care and severe stunting showed a significantly increased likelihood of developing severe pneumonia compared to those with pneumonia. Severe pneumonia in children occurred more often in older children who presented commonly from wealthy quintile families, and who often sought care from private facilities in urban settings. CONCLUSION AND RECOMMENDATION: Male sex, longer duration of illness, fever, received prior medical care, and severe stunting were significantly associated with development of WHO-defined severe childhood pneumonia in our population. The results of this study may help to develop interventions target to reduce childhood morbidity and mortality of children suffering from severe pneumonia.

Indexed as

Community-Acquired InfectionsPneumoniaBangladeshCase-Control StudiesChildFemaleGrowth DisordersHumansInfantMaleProspective Studies

Identifiers

PMID35320317
PMCPMC8942236
OpenAlexW4221114353

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.