Evidence map›Paper›PMID 35320092›Full record

ArticleIEEE transactions on medical imaging2022

Deep Relation Learning for Regression and Its Application to Brain Age Estimation.

Sheng He, Yanfang Feng, P Ellen Grant, Yangming Ou

Abstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
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  5. [Research progress on intelligent brain age prediction methods in diagnosis of Parkinson's disease].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
    Review
  6. Article
  7. Article
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  11. Review
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  13. Article
  14. Article
  15. Article
  16. Article
  17. Predicting the age of fieldScience advances · 2024
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sheng He
Yanfang Feng
P Ellen Grant
Yangming Ou

Funding

5/24 Healthy Brain and Child Development National ConsortiumU01DA055353 · NIDA · BOSTON CHILDREN'S HOSPITAL · PI Michelle A Bosquet Enlow, Patricia Ellen Grant · 2021 to 2026
$12.1M
Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI SCOTT Loren POMEROY, MUSTAFA SAHIN · 2021 to 2026
$9.4M
Longitudinal Study of childhood fMRI markers prior to reading onsetR01HD065762 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI GAAB, NADINE, GRANT, PATRICIA ELLEN · 2011 to 2021
$6.3M
Exploring the relationship between advanced multimodal brain MRI phenotypes, genes and cognitive outcome in adults with CHDR01HL152358 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI GRANT, PATRICIA ELLEN, GURVITZ, MICHELLE · 2021 to 2025
$3.9M
Novel MRI Assessment of Placental Structure and Function Throughout PregnancyR01HD100009 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI ADALSTEINSSON, ELFAR, GRANT, PATRICIA ELLEN · 2019 to 2023
$3.6M
Fetal MRI: robust self-driving brain acquisition and body movement quantificationR01EB032708 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI ADALSTEINSSON, ELFAR, GRANT, PATRICIA ELLEN · 2022 to 2025
$2.8M
Consortium Of MRI Biomarkers In Neonatal Encephalopathy (COMBINE)R61NS126792 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI COTTEN, CHARLES MICHAEL, GRANT, PATRICIA ELLEN · 2022 to 2024
$2.7M
Consortium Of MRI Biomarkers In Neonatal Encephalopathy (COMBINE)R33NS126792 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI CHARLES Michael COTTEN, Patricia Ellen Grant · 2025 to 2026
$1.8M
Neural Substrate of Outcomes after Neonatal Hypoxic Ischemic EncephalopathyR21NS121735 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI OU, YANGMING · 2022 to 2023
$504k
Brain MRI to pre-symptomatically predict seizure onset for Sturge-Weber SyndromeR21TR004265 · NCATS · BOSTON CHILDREN'S HOSPITAL · PI COMI, ANNE M, OU, YANGMING · 2022 to 2023
$479k
Multi-Site Clinical Data to Power MRI Biomarker of Neonatal Brain InjuryR03HD104891 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI OU, YANGMING · 2021 to 2022
$190k
Multi-site Data for Nutrition Studies in Healthy Early ChildhoodR03HD107124 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI OU, YANGMING · 2022 to 2023
$177k
NCATS NIH HHS R21 TR004265NHLBI NIH HHS R01 HL152358NIBIB NIH HHS R01 EB032708NICHD NIH HHS P50 HD105351NICHD NIH HHS R01 HD065762NICHD NIH HHS R01 HD100009NICHD NIH HHS R03 HD104891NICHD NIH HHS R03 HD107124NIDA NIH HHS U01 DA055353NINDS NIH HHS R21 NS121735NINDS NIH HHS R33 NS126792NINDS NIH HHS R61 NS126792
6 · The paper itself

Abstract

Most deep learning models for temporal regression directly output the estimation based on single input images, ignoring the relationships between different images. In this paper, we propose deep relation learning for regression, aiming to learn different relations between a pair of input images. Four non-linear relations are considered: "cumulative relation," "relative relation," "maximal relation" and "minimal relation." These four relations are learned simultaneously from one deep neural network which has two parts: feature extraction and relation regression. We use an efficient convolutional neural network to extract deep features from the pair of input images and apply a Transformer for relation learning. The proposed method is evaluated on a merged dataset with 6,049 subjects with ages of 0-97 years using 5-fold cross-validation for the task of brain age estimation. The experimental results have shown that the proposed method achieved a mean absolute error (MAE) of 2.38 years, which is lower than the MAEs of 8 other state-of-the-art algorithms with statistical significance (p<0.05) in paired T-test (two-side).

Indexed as

Deep LearningAdolescentAdultAgedAged, 80 and overAlgorithmsBrainChildChild, PreschoolHumansInfantInfant, NewbornMiddle AgedNeural Networks, ComputerSeizuresYoung Adult

Identifiers

PMID35320092
PMCPMC9782832

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.