Evidence map›Paper›PMID 35319987›Full record

ArticleScience advances2022

Small RNAs couple embryonic developmental programs to gut microbes.

Hayao Ohno, Zhirong Bao

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. An ultra-rapid mounting method formicroPublication biology · 2026
    Article
  4. Article
  5. Delineating the mechanisms and design principles ofComputational and structural biotechnology journal · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hayao OhnoDevelopmental Biology Program, Sloan Kettering Institute, New York, NY 10065, USA.ORCID 0000-0003-2635-6964
Zhirong BaoDevelopmental Biology Program, Sloan Kettering Institute, New York, NY 10065, USA.ORCID 0000-0002-2201-2745
Kettering University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
The Ubiquitin-Proteasome System in Metazoan EmbryogenesisR01GM097576 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI BAO, ZHIRONG · 2011 to 2020
$3.3M
NCI NIH HHS P30 CA008748NIGMS NIH HHS R01 GM097576NIH HHS P40 OD010440
6 · The paper itself

Abstract

Embryogenesis has long been known for its robustness to environmental factors. Although developmental tuning of embryogenesis to the environment experienced by the parent may be beneficial, little is understood on whether and how developmental patterns proactively change. Here, we show that

Indexed as

Caenorhabditis elegans ProteinsGastrointestinal MicrobiomeMicroRNAsAnimalsCaenorhabditis elegansCell DivisionEmbryonic DevelopmentGene Expression Regulation, DevelopmentalCaenorhabditis elegans ProteinsMicroRNAsMIRN35 microRNA, C elegans

Identifiers

PMID35319987
PMCPMC8942359
OpenAlexW4220734235

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.