ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022
Fiber-Optic Theranostics (FOT): Interstitial Fiber-Optic Needles for Cancer Sensing and Therapy.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 85 citations in OpenAlex.
- Recent advances in interstitial fluid dynamics for diagnostic, targeted drug delivery and precision medicine applications.Drug delivery and translational research · 2026Review
- Quantum Photothermal Self-Monitoring Fiber Probes for In Vivo Photothermal Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Intrinsically Disordered Polypeptides-Based Stealth Materials Enable Enhanced Photothermal Cancer Therapy Using an In Situ Fiber-Based Penetrating Laser System.Small science · 2026Article
- A novel photosensitizer-based photodynamic therapy reprograms the Kynurenine-AhR axis to boost antitumor immunity in breast cancer.Redox biology · 2026Article
- Application of fiber bragg grating sensing to thermal variation during dental implant site preparation: an in vitro study.BMC oral health · 2026Article
- Multifunctional fiber-optic theranostic probe for closed-loop tumor photothermal therapy.Light, science & applications · 2026Article
- Biodegradable and biocompatible poly(lactic acid) optical fibers for fiber-guided photothermal therapy of breast cancer cells in vitro.Biomedical optics express · 2026Article
- Evanescent wave-based optical biosensors for innovations, medical application and future perspectives.Journal of advanced research · 2026Review
- A Doubly Caged Bis(salicylamide)-Based Anion Transporter for Phototriggered Breast Cancer Therapy.ACS omega · 2026Article
- Spatiotemporal Mapping of Tumor Microenvironment Remodeling During Fiber-Optic Photothermal Therapy: A Multiparametric MRI Study in 4T1 Breast Cancer Xenografts.Chemical & biomedical imaging · 2026Article
- A tactile gripper on an optical fiber for perception and actuation.Nature communications · 2025Article
- High-power organic light-emitting diodes for photodynamic therapy in a mouse model of oral squamous cell carcinoma.Biomedical optics express · 2025Article
- Avenues for integrating photothermal therapy in cancer clinic.Communications chemistry · 2025Review
- Identification and removal of system-induced autofluorescence in miniaturized fiber-optic fluorescence endoscopes.PNAS nexus · 2025Article
- Comprehensive Analysis of Advancement in Optical Biosensing Techniques for Early Detection of Cancerous Cells.Biosensors · 2025Review
- Integrating Tumor Hypoxic Sensing and Photothermal Therapy Using a Miniaturized Fiber-Optic Theranostic Probe.Small science · 2025Article
- Fast detection of protein kinase B in chrysin treated colorectal cancer cells using a novel multicore microfiber biosensor.Communications engineering · 2024Article
- Fiber-optic drug delivery strategy for synergistic cancer photothermal-chemotherapy.Light, science & applications · 2024Article
- Bioluminescent Systems for Theranostic Applications.International journal of molecular sciences · 2024Review
- Radiation Damage Mechanisms and Research Status of Radiation-Resistant Optical Fibers: A Review.Sensors (Basel, Switzerland) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
Photonics has spurred a myriad of diagnostic and therapeutic applications for defeating cancer owing to its superiority in spatiotemporal maneuverability and minimal harm. The limits of light penetration depth and elusiveness of photosensitizer utilization, however, impede the implementation of the photodiagnostic and -therapy for determining and annihilating the deep-situated tumor. Herein, a promising strategy that harnesses functional optical fibers is developed and demonstrated to realize an in vivo endoscopic cancer sensing and therapy ensemble. Tumor detection is investigated using hypoxia-sensitive fluorescent fibers to realize fast and accurate tumor recognition and diagnosis. The tumor treatment is further performed by exploiting the endogenous photothermal effect of rare-earth-doped optical fibers. The eradication of orthotopic and subcutaneous xenografts significantly validates the availability of tumoricidal fibers. The strategy opens horizons to inspire the design of optical fiber-mediated "plug and play" precise tumor theranostics with high safety, which may intrigue broader fields, such as fiber optics, materials, chemistry, medicine, and clinics.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.