Evidence map›Paper›PMID 35319247›Full record

ArticleMicrobiology spectrum2022

PM10 and Other Climatic Variables Are Important Predictors of Seasonal Variability of Coccidioidomycosis in Arizona.

Daniel R Kollath, Joseph R Mihaljevic, Bridget M Barker

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

  1. Urban soils along the Kern River and Los Gatos Creek are hotspots forApplied and environmental microbiology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Urban soils along the Kern River and Los Gatos Creek are hotspots forbioRxiv : the preprint server for biology · 2026
    Article
  6. In Vitro Assessment ofGlobal challenges (Hoboken, NJ) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. From soil to clinic: current advances in understandingMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  14. Article
  15. Article
  16. Risk of Exposure toMicroorganisms · 2023
    Article
  17. Coccidioides Species: A Review of Basic Research: 2022.Journal of fungi (Basel, Switzerland) · 2022
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Daniel R KollathPathogen and Microbiome Institute, Northern Arizona Universitygrid.261120.6, Flagstaff, Arizona, USA.
Joseph R MihaljevicSchool of Informatics, Computing, and Cyber Systems, Northern Arizona Universitygrid.261120.6, Flagstaff, Arizona, USA.
Bridget M BarkerPathogen and Microbiome Institute, Northern Arizona Universitygrid.261120.6, Flagstaff, Arizona, USA.ORCID 0000-0002-3439-4517
Northern Arizona University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coccidioidomycosis (Valley fever) is a disease caused by the fungal pathogens Coccidioides immitis and Coccidioides posadasii that are endemic to the southwestern United States and parts of Mexico and South America. Throughout the range where the pathogens are endemic, there are seasonal patterns of infection rates that are associated with certain climatic variables. Previous studies that looked at annual and monthly relationships of coccidioidomycosis and climate suggest that infection numbers are linked with precipitation and temperature fluctuations; however, these analytic methods may miss important nonlinear, nonmonotonic seasonal relationships between the response (Valley fever cases) and explanatory variables (climate) influencing disease outbreaks. To improve our current knowledge and to retest relationships, we used case data from three counties of high endemicity in southern Arizona paired with climate data to construct a generalized additive statistical model that explores which meteorological parameters are most useful in predicting Valley fever incidence throughout the year. We then use our model to forecast the pattern of Valley fever cases by month. Our model shows that maximum monthly temperature, average PM10, and total precipitation 1 month prior to reported cases (lagged model) were all significant in predicting Valley fever cases. Our model fits Valley fever case data in the region of endemicity of southern Arizona and captures the seasonal relationships that predict when the public is at higher risk of being infected. This study builds on and retests relationships described by previous studies regarding climate variables that are important for predicting risk of infection and understanding this fungal pathogen.

Indexed as

CoccidioidomycosisAnimalsArizonaCoccidioidesHumansMammalsSeasonsUnited StatesclimateCoccidioidescoccidioidomycosisdisease ecologyGAMgeneralized additive modelhuman fungal pathogenmycologyValley fever

Identifiers

PMID35319247
PMCPMC9045372
OpenAlexW4220966977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.