Evidence map›Paper›PMID 35319233›Full record

ArticlemBio2022

Reevaluation of whether a Functional Agr-like Quorum-Sensing System Is Necessary for Production of Wild-Type Levels of Epsilon-Toxin by Clostridium perfringens Type D Strains.

Iman Mehdizadeh Gohari, Jihong Li, Julian I Rood, Bruce A McClane

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Iman Mehdizadeh GohariDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh Pennsylvania, USA.
Jihong LiDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh Pennsylvania, USA.
Julian I RoodInfection Program, Monash Biomedicine Discovery Institute, Department of Microbiology, Monash University, Victoria, Australia.
Bruce A McClaneDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh Pennsylvania, USA.ORCID 0000-0003-2451-5140
University of Pittsburgh · USMonash University · AU

Funding

Evaluating the Clostridium perfringens Agr-like Quorum Sensing System as a Therapeutic TargetR21AI140010 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MC CLANE, BRUCE A, UZAL, FRANCISCO A · 2018 to 2019
$445k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R21AI 140010-02NIAID NIH HHS R21 AI140010
6 · The paper itself

Abstract

Clostridium perfringens type B and D strains produce epsilon-toxin (ETX). Our 2011

Indexed as

Clostridium perfringensGene Expression Regulation, BacterialBlotting, WesternQuorum SensingVirulence

Identifiers

PMID35319233
PMCPMC9040827
OpenAlexW4220682904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.