Evidence map›Paper›PMID 35319117›Full record

ArticleJournal of veterinary internal medicine2022

Myoclonus in older Cavalier King Charles Spaniels.

Carina Rotter, Danielle Whittaker, Clare Rusbridge

Abstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Myoclonus as a neurologic manifestation of hypoglycemia in dogs.Journal of veterinary internal medicine · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Myoclonus in older Cavalier King Charles Spaniels.Journal of veterinary internal medicine · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Carina RotterOrthopedics and Neurology, Fitzpatrick Referrals Ltd, Surrey, United Kingdom.ORCID https://orcid.org/0000-0002-9032-3510
Danielle WhittakerOrthopedics and Neurology, Fitzpatrick Referrals Ltd, Surrey, United Kingdom.ORCID https://orcid.org/0000-0003-0240-8141
Clare RusbridgeOrthopedics and Neurology, Fitzpatrick Referrals Ltd, Surrey, United Kingdom.ORCID https://orcid.org/0000-0002-3366-2110

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMyoclonus is observed in older Cavalier King Charles Spaniels (CKCS) but a full description is lacking.

objectivesThe presence, age of onset, characteristics and treatment of myoclonic episodes were retrospectively evaluated in a cohort of CKCS which presented to 1 board-certified neurologist. Clinical data, imaging studies, presence of seizures and their management, as well as other comorbidities were noted. ANIMALS: Thirty-nine CKCS that were presented to 2 institutions between 2001 and 2018 with signs consistent with myoclonus. Clinical examination, blood sampling, advanced diagnostic imaging, cerebrospinal fluid analysis, and record keeping of other comorbidities was performed.

methodsThis is a retrospective case series, describing the presence of myoclonus in CKCS.

resultsClinical signs reported were spontaneous in onset, lasted a few seconds and consisted of rapid blinking with head nodding and variable extension down the thoracic limbs. Myoclonus occasionally led to stumbling of the thoracic limbs or collapse. Mean age of onset was 8.38 years (SD ±1.96). Thirteen of 39 dogs with myoclonus had paroxysmal events, such as generalized seizures (9/13). CONCLUSIONS AND CLINICAL IMPORTANCE: Myoclonus occurs in middle-aged to older CKCS and seems to be another epiphenomena of this breed. A link to epilepsy might be present.

Indexed as

Dog DiseasesMyoclonusAnimalsDogsHumansRetrospective StudiesSeizuresinvoluntary movementlevetiracetammyoclonic epilepsynonrhythmic muscle twitchingprimary progressive myoclonus of aging

Identifiers

PMID35319117
PMCPMC9151451

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.