ArticleInternational journal of clinical oncology2022
Survival after minimally invasive vs. open radical nephrectomy for stage I and II renal cell carcinoma.
Article in International journal of clinical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Outcomes of robotic-assisted surgery for pediatric renal tumors: a systematic review.Journal of robotic surgery · 2025Pooled it
- Comparative outcomes of robot-assisted, laparoscopic, and open radical nephrectomy: A Taiwan population-based study.Journal of robotic surgery · 2025Article
- [Our initial experience with robot-assisted partial nephrectomy].Magyar onkologia · 2024Article
- Impact of No-Clamping Partial Nephrectomy on Early Estimated Glomerular Filtration Rate Preservation.Journal of clinical medicine · 2024Article
- Review
- Development and validation of a nomogram to predict recurrence for clinical T1/2 clear cell renal cell carcinoma patients after nephrectomy.BMC surgery · 2024Article
- The Effect of Epidural Analgesia on Quality of Recovery (QoR) after Open Radical Nephrectomy: Randomized, Prospective, and Controlled Trial.Journal of personalized medicine · 2024Article
- Nephrectomies in Saudi Arabia: A Comprehensive Analysis of Outcomes from a High-Volume Minimally Invasive Surgery Center.Journal of kidney cancer and VHL · 2024Article
- Outcomes of Localized Renal Cell Carcinoma Across Different Races.Clinical medicine & research · 2023Article
- Primary renal mucinous adenocarcinoma masquerading as a giant renal cyst: a case report.Frontiers in oncology · 2023Article
- Comparison of 1-Year Health Care Expenditures and Utilization Following Minimally Invasive vs Open Nephrectomy.JAMA network open · 2022Article
- Propensity-matched pair analysis of safety and efficacy between laparoscopic and open radical nephrectomy for the treatment of large renal masses (>10 cm): a retrospective cohort study.Translational andrology and urology · 2022Article
- Clinical Profile and Outcome of Patients Operated on for Renal Cell Carcinoma: Experience from a Tertiary Care Center in a Developing Country.Research and reports in urology · 2022Article
- Renal cell cancer treatment: the Latin American Cooperative Oncology Group (LACOG) and the Latin American Renal Cancer Group (LARCG) surgery-focused consensus update.Therapeutic advances in urologyReview
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8 authors at 2 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundA recently reported phase III randomized trial comparing open and minimally invasive hysterectomy showed significantly higher rates of local recurrence after minimally invasive surgery (MIS) for cervical cancer. This raised concerns regarding patterns of recurrences and survival after MIS in general. This study aims to determine the effect of MIS on all-cause mortality among patients undergoing radical nephrectomy for Stage I and II renal cell carcinoma (RCC).
methodsWe utilized the National Cancer Database to identify patients diagnosed with clinical stage I-II RCCs between 2010 and 2013. Patients for whom a laparoscopic or robotic radical nephrectomy was attempted were compared to patients who underwent open radical nephrectomy (ORN). Adjusted regression models with inverse probability propensity score weighting (IPW) were utilized to identify independent predictors of receiving MIS. All-cause mortality rates were compared using IPW survival functions and log-rank tests. Adjusted Cox proportional hazard models were fitted to determine independent predictors of OS.
results27,642 patients were identified; 11,524 (41.7%) had MIS, while 16,118 (58.3%) had ORN. Kaplan-Meier survival curves in the IPW cohort showed significant OS advantage for patients who underwent MIS (p < 0.001). Furthermore, length of hospital stays (3 vs. 4 days), 30 day readmission rates (2.4 vs. 2.87%), 30 day (0.53 vs. 0.96%) and 90 day mortality rates (1.04 vs. 1.77%) were significantly higher in the ORN group (p < 0.001).
conclusionsMIS was associated with better OS outcomes compared to ORN for stage I and II RCC. In addition, MIS had lower post-operative readmission, 30- and 90 day mortality rates.
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