Evidence map›Paper›PMID 35318957›Full record

ArticleJournal of neurointerventional surgery2023

Bifurcation occlusions and endovascular treatment outcome in acute ischemic stroke.

Nerea Arrarte Terreros, Agnetha A E Bruggeman, Henk van Voorst, Praneeta R Konduri, Ivo G H Jansen, Manon Kappelhof, Manon L Tolhuisen, Nikki Boodt, Diederik W J Dippel, Aad van der Lugt and 10 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurointerventional surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 1 country.

Nerea Arrarte TerrerosDepartment of Biomedical Engineering and Physics, Amsterdam UMC, location AMC, Amsterdam, The Netherlands n.arrarteterreros@amsterdamumc.nl.ORCID 0000-0002-9912-7508
Agnetha A E BruggemanDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.ORCID 0000-0002-6873-2545
Henk van VoorstDepartment of Biomedical Engineering and Physics, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.ORCID 0000-0002-2647-3557
Praneeta R KonduriDepartment of Biomedical Engineering and Physics, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.
Ivo G H JansenDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.
Manon KappelhofDepartment of Biomedical Engineering and Physics, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.ORCID 0000-0001-5250-8955
Manon L TolhuisenDepartment of Biomedical Engineering and Physics, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.ORCID 0000-0002-2695-1117
Nikki BoodtDepartment of Neurology, Erasmus MC, Rotterdam, The Netherlands.
Diederik W J DippelDepartment of Neurology, Erasmus MC, Rotterdam, The Netherlands.ORCID 0000-0002-9234-3515
Aad van der LugtDepartment of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.
Wim H van ZwamDepartment of Radiology, Maastricht UMC, Maastricht, The Netherlands.ORCID 0000-0003-1631-7056
Robert J van OostenbruggeDepartment of Neurology, Maastricht UMC, Maastricht, The Netherlands.
H Bart van der WorpDepartment of Neurology and Neurosurgery Brain Center, UMC Utrecht, Utrecht, The Netherlands.
Bart J EmmerDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.
Frederick J A MeijerDepartment of Medical Imaging, Radboud UMC, Nijmegen, The Netherlands.
Yvo B W E M RoosDepartment of Neurology, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.
Ed van BavelDepartment of Biomedical Engineering and Physics, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.
Henk A MarqueringDepartment of Biomedical Engineering and Physics, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.
Charles B L M MajoieDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.
MR CLEAN Registry investigators
Amsterdam University Medical Centers · NLErasmus MC · NLMaastricht University Medical Centre · NLRadboud University Nijmegen · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA thrombus in the M1 segment of the middle cerebral artery (MCA) can occlude this main stem only or extend into the M1-M2 bifurcation. The occlusion pattern may affect endovascular treatment (EVT) success, as a bifurcated thrombus may be more prone to fragmentation during retrieval.

objectiveTo investigate whether bifurcated thrombus patterns are associated with EVT procedural and clinical outcomes.

methodsOcclusion patterns of MCA thrombi on CT angiography from MR CLEAN Registry patients were classified into three groups: main stem occlusion, bifurcation occlusion extending into one M2 branch, and bifurcation occlusion extending into both M2 branches. Procedural parameters, procedural outcomes (reperfusion grade and embolization to new territory), and clinical outcomes (24-48 hour National Institutes of Health Stroke Scale [NIHSS

resultsWe identified 1023 patients with an MCA occlusion of whom 370 (36%) had a main stem occlusion, 151 (15%) a single branch, and 502 (49%) a double branch bifurcation occlusion. There were no statistically significant differences in retrieval method, procedure time, number of retrieval attempts, reperfusion grade, and embolization to new territory between occlusion patterns. Patients with main stem occlusions had lower NIHSS

conclusionsIn our population, EVT procedural and long-term clinical outcomes were similar for MCA bifurcation occlusions and MCA main stem occlusions.

Indexed as

Ischemic StrokeStrokeHumansInfarction, Middle Cerebral ArteryMiddle Cerebral ArteryTreatment OutcomeUnited StatesCT AngiographyStentStrokeThrombectomy

Identifiers

PMID35318957
PMCPMC10086510
OpenAlexW4220737240

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.