Evidence map›Paper›PMID 35318931›Full record

ArticleEmerging infectious diseases2022

In Vitro Confirmation of Artemisinin Resistance in Plasmodium falciparum from Patient Isolates, Southern Rwanda, 2019.

Welmoed van Loon, Rafael Oliveira, Clara Bergmann, Felix Habarugira, Jules Ndoli, Augustin Sendegeya, Claude Bayingana, Frank P Mockenhaupt

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 35 citations in OpenAlex.

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  17. Temporal genomic analysis ofmedRxiv : the preprint server for health sciences · 2024
    Article
  18. Review
  19. Article
  20. Plasmodium vivax Malaria in Duffy-Positive Patients in Rwanda.The American journal of tropical medicine and hygiene · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Welmoed van Loon
Rafael Oliveira
Clara Bergmann
Felix Habarugira
Jules Ndoli
Augustin Sendegeya
Claude Bayingana
Frank P Mockenhaupt
Charité - Universitätsmedizin Berlin · DEUniversity of Rwanda · RWUniversity Teaching Hospital of Butare · RW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artemisinin resistance in Plasmodium falciparum is conferred by mutations in the kelch 13 (K13) gene. In Rwanda, K13 mutations have increased over the past decade, including mutations associated with delayed parasite clearance. We document artemisinin resistance in P. falciparum patient isolates from Rwanda carrying K13 R561H, A675V, and C469F mutations.

Indexed as

AntimalarialsArtemisininsHumansPlasmodium falciparumProtozoan ProteinsRwandaAntimalarialsArtemisininsProtozoan Proteinsantimicrobial resistanceartemisinin resistanceKelch-13 gene mutationsmalariaparasitesPlasmodium falciparumRwandavector-borne infections

Identifiers

PMID35318931
PMCPMC8962885
OpenAlexW4220837555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.