Evidence map›Paper›PMID 35318412›Full record

ArticleScientific reports2022

Interferon-γ signal drives differentiation of T-bet

Piyawan Kochayoo, Pongsakorn Thawornpan, Kittikorn Wangriatisak, Siriruk Changrob, Chaniya Leepiyasakulchai, Ladawan Khowawisetsut, John H Adams, Patchanee Chootong

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 17 citations in OpenAlex.

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  13. Clonal redemption of B cells in cancer.Frontiers in immunology · 2023
    Article
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  15. Frontiers in immunology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Piyawan KochayooDepartment of Clinical Microbiology and Applied Technology, Faculty of Medical Technology, Mahidol University, Bangkok, 10700, Thailand.
Pongsakorn ThawornpanDepartment of Clinical Microbiology and Applied Technology, Faculty of Medical Technology, Mahidol University, Bangkok, 10700, Thailand.
Kittikorn WangriatisakDepartment of Clinical Microbiology and Applied Technology, Faculty of Medical Technology, Mahidol University, Bangkok, 10700, Thailand.
Siriruk ChangrobDepartment of Clinical Microbiology and Applied Technology, Faculty of Medical Technology, Mahidol University, Bangkok, 10700, Thailand.
Chaniya LeepiyasakulchaiDepartment of Clinical Microbiology and Applied Technology, Faculty of Medical Technology, Mahidol University, Bangkok, 10700, Thailand.
Ladawan KhowawisetsutDepartment of Parasitology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
John H AdamsDepartment of Global Health, University of South Florida, Tampa, FL, 33612, USA.
Patchanee ChootongDepartment of Clinical Microbiology and Applied Technology, Faculty of Medical Technology, Mahidol University, Bangkok, 10700, Thailand. pchooton@gmail.com.
Mahidol University · THUniversity of South Florida · US

Funding

Immunological characterization of the P. vivax DBPR01AI064478 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI ADAMS, JOHN H · 2006 to 2023
$9.6M
NIAID NIH HHS R01 AI064478
6 · The paper itself

Abstract

For development of a long-lasting protective malaria vaccine, it is crucial to understand whether Plasmodium-induced memory B cells (MBCs) or plasma cells develop and stably contribute to protective immunity, or on the contrary the parasite suppresses antibody responses by inducing MBC dysfunction. The expansion of T-bet

Indexed as

MalariaMalaria, VivaxB-LymphocytesHumansImmunoglobulin GImmunologic MemoryInterferon-gammaMemory B CellsPlasma CellsPlasmodium vivaxIFNG protein, humanImmunoglobulin GInterferon-gamma

Identifiers

PMID35318412
PMCPMC8941117
OpenAlexW4220808714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.