Evidence map›Paper›PMID 35318391›Full record

ArticleScientific reports2022

LMS parameters, percentile, and Z-score growth curves for axial length in Chinese schoolchildren in Wuhan.

Pablo Sanz Diez, Li-Hua Yang, Mei-Xia Lu, Wieland Kiess, Siegfried Wahl

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Gender and Refractive Error Stratified Ocular Biometry Percentile Curves in Indian School Children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  5. Axial Length Growth Reference Curves and LMS Parameters for Japanese Children and Adolescents Aged 4-20 Years: The TMM BirThree Cohort Study.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  6. Development of Palatal Growth Charts for Unilateral Cleft Lip and Palate Before Primary Single-Stage Repair.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  7. Corrected Percentile Curves to Track Myopisation-The Anyang Childhood Eye Study.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  8. IMI-2025 Digest.Investigative ophthalmology & visual science · 2025
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Pablo Sanz DiezInstitute for Ophthalmic Research, Eberhard Karls University Tuebingen, Elfriede-Aulhorn-Strasse 7, 72076, Tuebingen, Germany. pablo.sanzdiez@zeiss.com.ORCID 0000-0001-6242-1685
Li-Hua YangWuhan Center for Adolescent Poor Vision Prevention and Control, Wuhan, China.
Mei-Xia LuWuhan Commission of Experts for the Prevention and Control of Adolescent Poor Vision, Wuhan, China.
Wieland KiessLeipzig Research Center for Civilization Diseases (LIFE), Leipzig University, Leipzig, Germany.
Siegfried WahlInstitute for Ophthalmic Research, Eberhard Karls University Tuebingen, Elfriede-Aulhorn-Strasse 7, 72076, Tuebingen, Germany.
Carl Zeiss (Germany) · DELeipzig University · DEWuhan Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the ocular structural changes are fundamental to defining strategies for myopia prevention and management. This study aimed to establish age-gender specific normative LMS parameters for axial length to generate percentile and Z-score growth curves in a population of Chinese schoolchildren. A total of 14,760 individuals aged 6 to 15 years from Wuhan, central China, contributed to this study. The LMS method was used for the calculation of LMS parameters and the generation of percentile and Z-score growth curves for axial length. Growth curves derived from the LMS parameters were compared with those originally calculated. Axial elongation was age- and percentile-dependent. The highest elongation rate occurred at the 98th percentile in the range 6 to 9 years, being up to 1.46 mm in boys and 1.42 mm in girls. The largest differences between original and newly generated growth curves were detected at the 98th percentile at age 15; 0.78 mm (females) and 0.63 mm (males). Multinomial logistic regression and receiver operating characteristic analyses revealed Z-scores as a good predictor for estimating high myopia development. The axial length growth curves presented in this study provide a technically solid instrument that depicts the best description of physiological eye growth for Chinese schoolchildren aged 6 to 15 years.

Indexed as

MyopiaAdolescentAsian PeopleChildChinaCitiesFemaleHumansMaleReference ValuesROC Curve

Identifiers

PMID35318391
PMCPMC8941183
OpenAlexW4220840246

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.