Evidence map›Paper›PMID 35318357›Full record

ArticleScientific reports2022

Synthesis and assessment of copper-based nanoparticles as a surface coating agent for antiviral properties against SARS-CoV-2.

Agung Purniawan, Maria Inge Lusida, Royan Wafi Pujiyanto, Aldise Mareta Nastri, Adita Ayu Permanasari, Alfonsus Adrian Hadikusumo Harsono, Nur Hafidzah Oktavia, Sigit Tri Wicaksono, Jezzy Renova Dewantari, Rima Ratnanggana Prasetya and 4 more

Erratum issuedAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Engineering copper and copper-based materials for a post-antibiotic era.Frontiers in bioengineering and biotechnology · 2025
    Review
  6. Insight into the role of copper-based materials against the coronaviruses MHV-3, a model for SARS-CoV-2, during the COVID-19 pandemic.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Antiviral Activity of Zinc Oxide Nanoparticles against SARS-CoV-2.International journal of molecular sciences · 2023
    Article
  16. Article
  17. Article
  18. Tackling COVID-19 Using Antiviral Nanocoating's-Recent Progress and Future Challenges.Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems · 2023
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Agung Purniawan *Department of Materials and Metallurgical Engineering, Institut Teknologi Sepuluh Nopember, Surabaya, Indonesia.
Maria Inge Lusida *Institute of Tropical Disease, Indonesia-Japan Collaborative Research Center for Emerging and Re-Emerging Infectious Diseases, Universitas Airlangga, Surabaya, Indonesia.
Royan Wafi PujiyantoResearch Center for Advanced Materials and Nanotechnology, Institut Teknologi Sepuluh Nopember, Surabaya, Indonesia.
Aldise Mareta NastriInstitute of Tropical Disease, Indonesia-Japan Collaborative Research Center for Emerging and Re-Emerging Infectious Diseases, Universitas Airlangga, Surabaya, Indonesia.
Adita Ayu PermanasariInstitute of Tropical Disease, Indonesia-Japan Collaborative Research Center for Emerging and Re-Emerging Infectious Diseases, Universitas Airlangga, Surabaya, Indonesia.
Alfonsus Adrian Hadikusumo HarsonoInstitute of Tropical Disease, Indonesia-Japan Collaborative Research Center for Emerging and Re-Emerging Infectious Diseases, Universitas Airlangga, Surabaya, Indonesia.
Nur Hafidzah OktaviaResearch Center for Advanced Materials and Nanotechnology, Institut Teknologi Sepuluh Nopember, Surabaya, Indonesia.
Sigit Tri WicaksonoResearch Center for Advanced Materials and Nanotechnology, Institut Teknologi Sepuluh Nopember, Surabaya, Indonesia.
Jezzy Renova DewantariInstitute of Tropical Disease, Indonesia-Japan Collaborative Research Center for Emerging and Re-Emerging Infectious Diseases, Universitas Airlangga, Surabaya, Indonesia.
Rima Ratnanggana PrasetyaInstitute of Tropical Disease, Indonesia-Japan Collaborative Research Center for Emerging and Re-Emerging Infectious Diseases, Universitas Airlangga, Surabaya, Indonesia.
Krisnoadi RahardjoInstitute of Tropical Disease, Indonesia-Japan Collaborative Research Center for Emerging and Re-Emerging Infectious Diseases, Universitas Airlangga, Surabaya, Indonesia.
Mitsuhiro NishimuraCenter for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Japan.
Yasuko MoriCenter for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Japan.
Kazufumi ShimizuInstitute of Tropical Disease, Indonesia-Japan Collaborative Research Center for Emerging and Re-Emerging Infectious Diseases, Universitas Airlangga, Surabaya, Indonesia. shimizu.kazufumi@gmail.com.

Funding

the Japan Agency for Medical Research and Development (AMED) JP 21wm0125009
6 · The paper itself

Abstract

To halt the pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), governments around the world have imposed policies, such as lockdowns, mandatory mask wearing, and social distancing. The application of disinfecting materials in shared public facilities can be an additional measure to control the spread of the virus. Copper is a prominent material with antibacterial and antiviral effects. In this study, we synthesized copper nanoparticles (CuNPs) as a surface coating agent and assessed their antiviral activity against SARS-CoV-2. CuNPs with a mean size of 254 nm in diameter were synthesized from copper sulfate as a source and were predominantly composed of copper oxide. The synthesized CuNPs were mixed with resin-based paint (CuNP/paint) and sprayed on the surface of stainless steel remnants. SARS-CoV-2 lost 97.8% infectivity on the CuNP/paint-coated surface after 30 min of exposure and more than 99.995% infectivity after 1 h of exposure. The inactivation rate was approximately 36-fold faster than that on the paint alone-coated and uncoated surfaces. The CuNP/paint-coated surface showed powerful inactivation of SARS-CoV-2 infectivity, although further study is needed to elucidate the inactivation mechanisms. Applications of CuNP/paint coatings to public or hospital facilities and other commonly touched areas are expected to be beneficial.

Indexed as

COVID-19NanoparticlesAntiviral AgentsCommunicable Disease ControlCopperHumansSARS-CoV-2Antiviral AgentsCopper

Identifiers

PMID35318357
PMCPMC8941130

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.