Evidence map›Paper›PMID 35318288›Full record

ArticleGut and liver2022

Gut Microbiota Alteration Influences Colorectal Cancer Metastasis to the Liver by Remodeling the Liver Immune Microenvironment.

Na Yuan, Xiaoyan Li, Meng Wang, Zhilin Zhang, Lu Qiao, Yamei Gao, Xinjian Xu, Jie Zhi, Yang Li, Zhongxin Li and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Gut and liver, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 68 citations in OpenAlex.

  1. Review
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  3. Cells · 2026
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  17. Gut Commensal Antibiotic-ResistantResearch (Washington, D.C.) · 2025
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Na YuanDepartment of Oncology, Hebei Medical University, Shijiazhuang, China.ORCID 0000-0001-6268-6106
Xiaoyan LiThe Third Department of Oncology, Hebei General Hospital, Shijiazhuang, China.ORCID 0000-0001-8466-4135
Meng WangDepartment of Clinical Psychology, Baoding No.1 Central Hospital, Baoding, China.ORCID 0000-0002-4739-1884
Zhilin ZhangDepartment of Radiotherapy, The First Affiliated Hospital of Hebei North University, Zhangjiakou, China.ORCID 0000-0003-1976-2462
Lu QiaoThe Third Department of Oncology, Hebei General Hospital, Shijiazhuang, China.ORCID 0000-0003-1344-7859
Yamei GaoThe Third Department of Oncology, Hebei General Hospital, Shijiazhuang, China.ORCID 0000-0002-6913-538X
Xinjian XuDepartment of Thoracic Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.ORCID 0000-0002-5138-5719
Jie ZhiThe Third Department of Oncology, Hebei General Hospital, Shijiazhuang, China.ORCID 0000-0003-1727-7746
Yang LiDepartment of Oncology, Affiliated Hospital of Hebei University, Baoding, China.ORCID 0000-0001-9245-6547
Zhongxin LiDepartment of General Surgery, The First Hospital of Hebei Medical University, Shijiazhuang, China.ORCID 0000-0002-6375-1667
Yitao JiaDepartment of Oncology, Hebei Medical University, Shijiazhuang, China.ORCID 0000-0003-2610-9330
Hebei General Hospital · CNHebei Medical University · CNAffiliated Hospital of Hebei University · CNBaoding People's Hospital · CNHebei North University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aims: This study aimed to explore the effect of gut microbiota-regulated Kupffer cells (KCs) on colorectal cancer (CRC) liver metastasis. Methods: A series of Results: Fewer liver metastases were identified in the ampicillin-streptomycin-colistin and colistin groups. Increased proportions of Conclusions: An increased abundance of

Indexed as

Colorectal NeoplasmsGastrointestinal MicrobiomeLiverLiver NeoplasmsTumor MicroenvironmentAmpicillinColistinHumansStreptomycinVancomycinAmpicillinColistinStreptomycinVancomycinColorectal neoplasmsGastrointestinal microbiomeKupffer cellsLiver metastasis

Identifiers

PMID35318288
PMCPMC9289841
OpenAlexW4220935697

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.