Evidence map›Paper›PMID 35318199›Full record

ArticleBMJ case reports2022

Oesophageal and pulmonary invasive aspergillosis in a patient with multiple myeloma.

Alfredo G Puing, Justine Ross, Vishwas Parekh, Deepa D Nanayakkara

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Infective Esophagitis.The Korean journal of helicobacter and upper gastrointestinal research · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alfredo G PuingDivision of Infectious Diseases, Department of Medicine, City of Hope National Medical Center, Duarte, California, USA alfredopuing@gmail.com.ORCID http://orcid.org/0000-0002-9836-4835
Justine RossDepartment of Pharmacy Services, City of Hope National Medical Center, Duarte, California, USA.
Vishwas ParekhDepartment of Pathology, City of Hope National Medical Center, Duarte, California, USA.
Deepa D NanayakkaraDivision of Infectious Diseases, Department of Medicine, City of Hope National Medical Center, Duarte, California, USA.
City Of Hope National Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive aspergillosis (IA) is a serious fungal infection that primarily affects patients with prolonged and profound neutropenia, and compromised cell-mediated immunity. Aspergillosis of the oesophagus and gastrointestinal tract is uncommon but seen in advanced cases of disseminated IA. However, it is difficult to diagnose antemortem due to the poor specificity of the symptoms and the absence of characteristic imaging findings. Therefore, the reported cases of gastrointestinal aspergillosis have been associated with high morbidity and mortality, and frequently diagnosed postmortem. Here we present a successful outcome in a patient with relapsed and refractory multiple myeloma who had presented with febrile neutropenia, cough and dysphagia, and was diagnosed with disseminated IA comprising of pulmonary and oesophageal involvement. This case highlights the need for a high index of suspicion and the importance of invasive procedures for histopathology and molecular diagnostics to ensure an early diagnosis and therapeutic intervention.

Indexed as

AspergillosisInvasive Fungal InfectionsInvasive Pulmonary AspergillosisMultiple MyelomaEsophagusHumansinfection (gastroenterology)infectious diseasespneumonia (infectious disease)

Identifiers

PMID35318199
PMCPMC8943765
OpenAlexW4220745716

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.