Evidence map›Paper›PMID 35317845›Full record

ReviewInfectious agents and cancer2022

Chlamydia pneumoniae infections and development of lung cancer: systematic review.

Nadeesha Madushani Premachandra, J A A Sampath Jayaweera

Open access · goldAbstract readReview
In one paragraph

Review in Infectious agents and cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Microbiota in cancer: current understandings and future perspectives.Signal transduction and targeted therapy · 2026
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  19. Alternative strategies forFrontiers in microbiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nadeesha Madushani PremachandraDepartment of Microbiology, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri Lanka.
J A A Sampath JayaweeraDepartment of Microbiology, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri Lanka. jaas071@gmail.com.ORCID http://orcid.org/0000-0001-5051-530X
Rajarata University of Sri Lanka · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChlamydia pneumoniae is an obligate intracellular pathogen and is a common cause of human respiratory diseases, including pneumonia. It has been already known to have a causal relationship with some chronic diseases such as chronic obstructive pulmonary disease, asthma, and atherosclerotic cardiovascular diseases. In this review, we aim to find out the association between C. pneumoniae infection and lung cancer.

methodsThis is a systematic review on C. pneumoniae infection and the development of lung cancer, based on published articles consolidated from PubMed and Google Scholar on the topic.

resultsOut of 46 articles, 27 were selected and screened through the process. Twenty-four articles positively supported the hypothesis with one animal model, while 3 of them were negatively supportive. Several proposed mechanisms explain the pathogenesis with some knowledge gaps.

conclusionAlthough some studies showed an association between C. pneumoniae infection and lung cancer, whether the C. pneumoniae infection is an individual risk factor for lung cancer is still debatable. And it needs further experimental studies on both humans and animals with large observational studies to better understand the association between C. pneumoniae infection and lung cancer.

Indexed as

Chlamydia pneumoniaeLung cancerRisk factorSerology

Identifiers

PMID35317845
PMCPMC8941765
OpenAlexW4220903654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.