Evidence map›Paper›PMID 35317791›Full record

ArticleBMC veterinary research2022

Pulmonary fibrosis in a dog as a sequela of infection with Severe Acute Respiratory Syndrome Coronavirus 2? A case report.

Barbara Colitti, Luca Manassero, Elena Colombino, Erica Ilaria Ferraris, Roberta Caccamo, Luigi Bertolotti, Alessio Bortolami, Francesco Bonfante, Valentina Papa, Giovanna Cenacchi and 5 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC veterinary research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Barbara ColittiDepartment of Veterinary Sciences, University of Turin, Turin, Italy. barbara.colitti@unito.it.ORCID http://orcid.org/0000-0002-3731-7031
Luca ManasseroDepartment of Veterinary Sciences, University of Turin, Turin, Italy.
Elena ColombinoDepartment of Veterinary Sciences, University of Turin, Turin, Italy.
Erica Ilaria FerrarisDepartment of Veterinary Sciences, University of Turin, Turin, Italy.
Roberta CaccamoDepartment of Veterinary Sciences, University of Turin, Turin, Italy.
Luigi BertolottiDepartment of Veterinary Sciences, University of Turin, Turin, Italy.
Alessio BortolamiIstituto Zooprofilattico Sperimentale Delle Venezie, Legnaro, Italy.
Francesco BonfanteIstituto Zooprofilattico Sperimentale Delle Venezie, Legnaro, Italy.
Valentina PapaDepartment of Biomedical and Neuromotor Sciences, "Alma Mater" University of Bologna, Bologna, Italy.
Giovanna CenacchiDepartment of Biomedical and Neuromotor Sciences, "Alma Mater" University of Bologna, Bologna, Italy.
Fiorella CalabreseDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova Medical School, Padua, Italy.
Elena BozzettaIstituto zooprofilattico Sperimentale del Piemonte, Liguria e valle d'Aosta, Turin, Italy.
Katia VarelloIstituto zooprofilattico Sperimentale del Piemonte, Liguria e valle d'Aosta, Turin, Italy.
Maria Teresa Capucchio *Department of Veterinary Sciences, University of Turin, Turin, Italy.
Sergio Rosati *Department of Veterinary Sciences, University of Turin, Turin, Italy.
University of Turin · ITIstituto Zooprofilattico Sperimentale delle Venezie · ITIstituto Zooprofilattico Sperimentale del Piemonte Liguria e Valle d'Aosta · ITUniversity of Bologna · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInterstitial lung disease is a heterogeneous group of conditions characterized by severe radiographic changes and clinicopathological findings. However, in the vast majority of cases, the cause remains unknown. CASE DESCRIPTION: In the present study, we reported the clinical case of a 3 years old female Bull Terrier presented in October 2020 to the Advanced Diagnostic Imaging Department of the Turin Veterinary Teaching Hospital with a progressive pulmonary illness characterized by dyspnea, exercise intolerance, and a diffuse and severe pulmonary interstitial pattern at imaging investigations. Considering the clinical findings, the dog was included in a serological survey for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in companion animals, showing positive results. Due to the further clinical worsening, the owners opted for euthanasia. At necroscopy, dog showed severe and chronic bronchopneumonia compatible with a Canine Idiopathic Pulmonary Fibrosis and with serological features linked to a SARS-CoV-2 infection.

conclusionsThe comparison of these lesions with those reported in humans affected by Coronavirus Disease 2019 (COVID-19) supports the hypothesis that these findings may be attributable to the post-acute sequelae of SARS-CoV-2 infection in a dog with breed predisposition to Canine Idiopathic Pulmonary Fibrosis (CIPF), although direct evidence of SARS-CoV-2 by molecular or antigenic approaches remained unsolved.

Indexed as

COVID-19Dog DiseasesAnimalsDogsFemaleHospitals, AnimalHospitals, TeachingHumansIdiopathic Pulmonary FibrosisPost-Acute COVID-19 SyndromeSARS-CoV-2COVID-19DiagnosisDogPneumoniaSARS-CoV-2

Identifiers

PMID35317791
PMCPMC8938595
OpenAlexW4220655567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.