Trial reportBMC neurology2022
Effectiveness of action observation therapy based on virtual reality technology in the motor rehabilitation of paretic stroke patients: a randomized clinical trial.
Trial report in BMC neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Action Observation Therapy Based on Virtual Reality Technology in Motor Rehabilitation of Paretic Stroke Patients: a Randomized Clinical Trial
Effects of Action Observation Therapy Based on Virtual Reality for Upper Extremity Rehabilitation in Stroke
Effects of Functional Action Observation Therapy With Rhythmic Auditory Cueing on Balance and Gait in Patients With Stroke
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Effect of Home-Based Virtual Reality Training on Upper Extremity Recovery in Patients With Stroke: Systematic Review.Journal of medical Internet research · 2025Pooled it
- A systematic review of functional near-infrared spectroscopy-based task paradigms in stroke rehabilitation.Frontiers in human neuroscience · 2025Pooled it
- Action Observation Combined With Virtual Reality Promotes Motor Recovery After Stroke: A Randomized Controlled Trial.Stroke · 2026Trial
- The effects of virtual reality-mediated tendon and nerve gliding exercises in the conservative management of carpal tunnel syndrome: a double-blind randomized placebo controlled trial.European journal of physical and rehabilitation medicine · 2024Trial
- Early sleep after action observation and motor imagery training boosts improvements in manual dexterity.Scientific reports · 2023Trial
- Quo Vadis, Amadeo Hand Robot? A Randomized Study with a Hand Recovery Predictive Model in Subacute Stroke.International journal of environmental research and public health · 2022Trial
- Optimizing Multidisciplinary Neurotraumatology Education in Thailand: Aptitude-Dependent Outcomes in Virtual Patient Simulation in Collaboration with the Academy for Multidisciplinary Neurotraumatology.Asian journal of neurosurgery · 2026Article
- The Moderating Role of Virtual Arm Embodiment for Upper Limb Rehabilitation in Stroke Patients with Proprioceptive Deficit: A Pilot Study.Behavioral sciences (Basel, Switzerland) · 2026Article
- Proprioceptive-augmented virtual reality influences the kinematic properties of movement imitation.Journal of neuroengineering and rehabilitation · 2026Article
- Action Observation Training for Upper Limb Stroke Rehabilitation: A Pilot Study on the Role of Attention.Journal of clinical medicine · 2025Article
- The Influence of Previous Experience on Virtual Reality Adoption in Medical Rehabilitation and Overcoming Knowledge Gaps Among Health Care Professionals: Qualitative Interview Study.Journal of medical Internet research · 2025Article
- Virtual body continuity during action observation affects motor cortical excitability.Scientific reports · 2025Article
- Psychological effects of virtual reality intervention on breast cancer patients with different personalities: A randomized controlled trial.International journal of nursing sciences · 2025Article
- Being in Virtual Reality and Its Influence on Brain Health-An Overview of Benefits, Limitations and Prospects.Brain sciences · 2024Review
- Effects of Virtual Reality-Based Mirror Therapy on Upper Extremity Motor Function, Manual Performance and Gross Manual Dexterity Among Stroke Patients: A Meta-Analysis.International journal of exercise science · 2024Review
- Article
- Exploring the efficacy of virtual reality-based rehabilitation in stroke: a narrative review of current evidence.Annals of medicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe rehabilitation of paretic stroke patients uses a wide range of intervention programs to improve the function of impaired upper limb. A new rehabilitative approach, called action observation therapy (AOT) is based on the discovery of mirror neurons and has been used to improve the motor functions of adult stroke patients and children with cerebral palsy. Recently, virtual reality (VR) has provided the potential to increase the frequency and effectiveness of rehabilitation treatment by offering challenging and motivating tasks.
methodsThe purpose of the present project is to design a randomized controlled six-month follow-up trial (RCT) to evaluate whether action observation (AO) added to standard VR (AO + VR) is effective in improving upper limb function in patients with stroke, compared with a control treatment consisting of observation of naturalistic scenes (CO) without any action content, followed by VR training (CO + VR). DISCUSSION: AO + VR treatment may provide an addition to the rehabilitative interventions currently available for recovery after stroke and could be utilized within standard sensorimotor training or in individualized tele-rehabilitation.
trial registrationThe trial has been prospectively registered on ClinicalTrials.gov. NCT05163210 . 17 December 2021.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.