ArticleWorld journal of gastrointestinal surgery2022
Nomograms predicting prognosis of patients with pathological stages T1N2-3 and T3N0 gastric cancer.
Article in World journal of gastrointestinal surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Preoperative serum prealbumin as a prognostic marker for survival after gallbladder cancer resection: a multicenter study.BMC gastroenterology · 2025Article
- Prognostic artificial intelligence model to predict 5 year survival at 1 year after gastric cancer surgery based on nutrition and body morphometry.Journal of cachexia, sarcopenia and muscle · 2023Article
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9 authors.
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Abstract
backgroundPatients with pathological stages T1N2-3 (pT1N2-3) and pT3N0 gastric cancer (GC) have not been routinely included in the target population for postoperative chemotherapy according to the Japanese Gastric Cancer Treatment Guideline, and their prognosis is significantly different.
aimTo identify the high-risk patients after radical surgery by analyzing biomarkers and clinicopathological features and construct prognostic models for them.
methodsA total of 459 patients with pT1N2-3/pT3N0 GC were retrospectively selected for the study. The Chi-square test was used to analyze the differences in the clinicopathological features between the pT1N2-3 and pT3N0 groups. The Kaplan-Meier analysis and log-rank test were used to analyze overall survival (OS). The independent risk factors for patient prognosis were analyzed by univariate and multivariate analyses based on the Cox proportional hazards regression model. The cutoff values of continuous variables were identified by receiver operating characteristic curve. The nomogram models were constructed with R studio.
resultsThere was no statistically significant difference in OS between the pT1N2-3 and pT3N0 groups (
conclusionNomogram model combining prealbumin, CEA, and mLNR levels can be used to predict the prognosis of pT1N2-3 GC. Nomogram model combining age, BMI, and gastrectomy can be used to predict the prognosis of pT3N0 GC.
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