Evidence map›Paper›PMID 35317540›Full record

ArticlePublic health action2022

Antibiotic resistance in patients with urinary tract infections in Pakistan.

M Bullens, A de Cerqueira Melo, S Raziq, J Lee, G G Khalid, S N Khan, A Zada, Atta-Ur-Rehman, Y Wailly, S M Zeshan and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Public health action, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Longitudinal trends in antibiotic resistance ofPakistan journal of medical sciences · 2025
    Article
  7. Molecular characterization of blaBMC infectious diseases · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Regional and National Trends in Consumption of Antimicrobials in Pakistan; Pre and Post-COVID (2019-2021).Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 5 countries.

M BullensTimurgara District Hospital Project, Médecins Sans Frontières Operational Centre Brussels (MSF OCB), Timurgara, Pakistan.
A de Cerqueira MeloTimurgara District Hospital Project, Médecins Sans Frontières Operational Centre Brussels (MSF OCB), Timurgara, Pakistan.
S RaziqTimurgara District Hospital Project, Médecins Sans Frontières Operational Centre Brussels (MSF OCB), Timurgara, Pakistan.
J LeeTimurgara District Hospital Project, Médecins Sans Frontières Operational Centre Brussels (MSF OCB), Timurgara, Pakistan.
G G KhalidMSF OCB, Islamabad Mission Coordination, Islamabad, Pakistan.
S N KhanTimurgara District Hospital Project, Médecins Sans Frontières Operational Centre Brussels (MSF OCB), Timurgara, Pakistan.
A ZadaTimurgara District Hospital Project, Médecins Sans Frontières Operational Centre Brussels (MSF OCB), Timurgara, Pakistan.
Atta-Ur-Rehman
Y WaillyOperations Department, MSF OCB, Brussels, Belgium.
S M ZeshanAga Khan Laboratory, Karachi, Pakistan.
N J SaadOperations Department, MSF OCB, Brussels, Belgium.
J Gil-CuestaMSF OCB, Medical Department, Brussels, Belgium.
A WilliamsLuxembourg Operational Research (LuxOR) Unit, MSF OCB, Luxembourg.
Médecins Sans Frontières · USAga Khan University · PKGovernment of Pakistan · PKInstitute of Business Leadership · PKMédecins Sans Frontières · LUMédecins Sans Frontières · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe level of antibiotic resistance of pathogens causing uncomplicated urinary tract infections (UTIs) is increasing. The 2017-2018 GLASS (Global Antimicrobial Resistance and Use Surveillance System) report indicated >70% resistance to ceftriaxone and ciprofloxacin in

methodsA prospective study was conducted in the Médecins Sans Frontières (MSF) supported Timurgara District Hospital, Timurgara, Pakistan, from September 2017 to December 2018. Women aged 18-65 years presenting to the Emergency Department with symptoms of uncomplicated UTI (cystitis/pyelonephritis) were invited to participate. We conducted microbiological culture and sensitivity testing for samples with positive dipstick or nitrite test.

resultsOf the 200 patients who participated, 109 (54.5%) were diagnosed with pyelonephritis and 91 (45.5%) with cystitis. Forty-three samples (21.5%) were culture-positive:

conclusionsThis study found resistance to first- and second-line antibiotics for treating UTIs as per the MSF protocol. Heightened awareness and potential changes to local prescription practices are necessary to curb the spread of antimicrobial resistance pathogens causing UTIs.

Indexed as

antibiotic resistancedeveloping countryemergency departmentEscherichia coliPakistanurinary tract infection

Identifiers

PMID35317540
PMCPMC8908872
OpenAlexW4220943379

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.