Evidence map›Paper›PMID 35317507›Full record

ArticleNoro psikiyatri arsivi2022

Optic Neuritis due to Use of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide: A Case Report.

Türkan Acar, Halil Alper Eryilmaz, Bilgehan Atilgan Acar, Ertuğrul Güçlü, Oğuz Karabay

Open access · greenAbstract readCase Reports
In one paragraph

Article in Noro psikiyatri arsivi, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Türkan AcarDepartment of Neurology, Sakarya University, Education and Research Hospital, Sakarya, Turkey.
Halil Alper EryilmazDepartment of Neurology, Sakarya University, Education and Research Hospital, Sakarya, Turkey.
Bilgehan Atilgan AcarDepartment of Neurology, Sakarya University, Education and Research Hospital, Sakarya, Turkey.
Ertuğrul GüçlüDepartment of Infectious Diseases, Sakarya University, Education and Research Hospital, Sakarya, Turkey.
Oğuz KarabayDepartment of Infectious Diseases, Sakarya University, Education and Research Hospital, Sakarya, Turkey.
Sakarya University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroophthalmic involvement may occur in people infected with primary human immunodeficiency virus (HIV) due to the infection itself, opportunistic infections, malignancy or due to vascular causes. However, treatment-related optic neuropathy may be considered in patients receiving Antiretroviral therapy (ART), without an identified etiological cause, despite all examinations. In this case report, a near-complete recovery was observed in vision loss of a patient, whose 4-month treatment regimen of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/FTC/TAF) was replaced with a combination of tenofovir disoproxil + emtricitabine and lopinavir+ritonavir due to the development of optic neuritis. Recognition of the present symptoms rapidly and the implementation of the necessary change is extremely important for preventing permanent damage in these patients.

Indexed as

antiretroviral therapyHIVoptic neuritis

Identifiers

PMID35317507
PMCPMC8895810
OpenAlexW3057747783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.