ArticleNoro psikiyatri arsivi2022
Effects of Energy Drink and Alcohol Mixed with Energy Drink on Pentylenetetrazol-Induced Seizures in Rats.
Article in Noro psikiyatri arsivi, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 3 citations in OpenAlex.
- Ethanol combined with energy drinks: Two decades of research in rodents.Frontiers in behavioral neuroscience · 2022Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Energy drink consumption is on an upswing with reportedly significant health problems associated with its consumption. Additionally, it is one of the most preferred products used in combination with alcohol. The present study aimed to investigate the effects of energy drink and alcohol mixed energy drink (AmED) on epileptic seizures. Methods: Adult female (250-350 g) Wistar rats were divided into five groups (n=8 for each group). Caffeine (3.43 mg/kg) was injected through the intraperitoneal (IP) route and alcohol (3.4 g/kg), energy drink (10.71 ml/kg), and AmED were given to the rats via intragastric intubation for 14 days. On the first, seventh, and fourteenth days of the experiment, pentylenetetrazole (PTZ) (60 mg/kg IP) was injected into the rats. The onset time and severity of seizures were evaluated immediately after PTZ. Results: Both caffeine and energy drink caused a significant decrease in the onset time of the seizures. Energy drink showed a significantly shorter onset time than caffeine on the seventh ( Conclusion: Our results suggest that energy drink and AmED produced some significant unfavorable effects on PTZ-induced seizures. They may be dangerous in patient with epilepsy and individuals prone to seizure.
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